Evidence map›Paper›PMID 30761257›Full record

ArticleFEBS open bio2019

Renal mineralocorticoid receptor expression is reduced in lipoatrophy.

Barbara Toffoli, Stella Bernardi, Carine Winkler, Coralie Carrascosa, Federica Gilardi, Béatrice Desvergne

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS open bio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. The mineralocorticoid receptor in diabetic kidney disease.American journal of physiology. Renal physiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Barbara ToffoliCenter for Integrative Genomics Faculty of Biology and Medicine University of Lausanne Switzerland.ORCID 0000-0002-6854-5782
Stella BernardiDepartment of Medical Sciences University of Trieste Italy.
Carine WinklerCenter for Integrative Genomics Faculty of Biology and Medicine University of Lausanne Switzerland.
Coralie CarrascosaCenter for Integrative Genomics Faculty of Biology and Medicine University of Lausanne Switzerland.
Federica GilardiCenter for Integrative Genomics Faculty of Biology and Medicine University of Lausanne Switzerland.
Béatrice DesvergneCenter for Integrative Genomics Faculty of Biology and Medicine University of Lausanne Switzerland.
Swiss Integrative Center for Human Health · CHUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a condition characterized by adipose tissue hypertrophy; it is estimated that the obesity epidemic accounted for 4 million deaths in 2015 and that 70% of these were due to cardiovascular disease (CVD). One of the mechanisms linking obesity to CVD is the ability of adipose tissue to secrete circulating factors. We hypothesized that adipose tissue and its secretory products may influence mineralocorticoid receptor (MR) expression. Here, we showed that expression of MR and its downstream targets (

Indexed as

AnimalsDisease Models, AnimalFemaleLeptinLipodystrophyMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicObesityReceptors, MineralocorticoidLeptinReceptors, Mineralocorticoidkidneylipoatrophymineralocorticoid receptorobesity

Identifiers

PMID30761257
PMCPMC6356154
OpenAlexW2906008520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.