ReviewFrontiers in microbiology2019
Evolution of Immune Systems From Viruses and Transposable Elements.
Review in Frontiers in microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 70 citations in OpenAlex.
- Position-dependent codon occurrence is associated with patterns of translational efficiency and ribosomal occupancy in the human transcriptome.PLoS computational biology · 2026Article
- Locust cGAS-like Receptors Recognize Derivatives of a Gypsy Retrotransposon to Synergize with RNAi Against Viral Invasion.Insects · 2026Article
- Persistent viral infection in the Drosophila fat body is associated with immune activation at the single cell level.BMC genomics · 2026Article
- The highly diverse repertoire of transposable elements within the genomes of parasitic wasps (Hymenoptera: Braconidae).Mobile DNA · 2025Article
- Dancing with the enemy: symbiotic relationships between plant RNA viruses and their hosts.Frontiers in plant science · 2025Review
- Experimental models for developing oncolytic virotherapy for metastatic prostate cancer.Frontiers in immunology · 2025Review
- Endogenous viral elements: insights into data availability and accessibility.Virus evolution · 2024Article
- Comparative Analysis of Transposable Elements Reveals the Diversity of Transposable Elements in Decapoda and Their Effects on Genomic Evolution.Marine biotechnology (New York, N.Y.) · 2023Article
- From parasites to partners: exploring the intricacies of host-transposon dynamics and coevolution.Functional & integrative genomics · 2023Review
- Characterization of an archaeal virus-host system reveals massive genomic rearrangements in a laboratory strain.Frontiers in microbiology · 2023Article
- Self-empowerment of life through RNA networks, cells and viruses.F1000Research · 2023Review
- Editorial for the Special Issue: The Role of the Virome in Health and Disease.Microorganisms · 2021Article
- The Baltimore Classification of Viruses 50 Years Later: How Does It Stand in the Light of Virus Evolution?Microbiology and molecular biology reviews : MMBR · 2021Review
- Defensive hypervariable regions confer superinfection exclusion in microviruses.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Non-Random Genome Editing and Natural Cellular Engineering in Cognition-Based Evolution.Cells · 2021Review
- Viroids and the Origin of Life.International journal of molecular sciences · 2021Review
- Systems Biology to Understand and Regulate Human Retroviral Proinflammatory Response.Frontiers in immunology · 2021Review
- Guardian of the Genome: An Alternative RAG/Transib Co-Evolution Hypothesis for the Origin of V(D)J Recombination.Frontiers in immunology · 2021Article
- Social Networking of Quasi-Species Consortia drive Virolution via Persistence.AIMS microbiology · 2021Review
- DRAM for distilling microbial metabolism to automate the curation of microbiome function.Nucleic acids research · 2020Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Virus-derived sequences and transposable elements constitute a substantial portion of many cellular genomes. Recent insights reveal the intimate evolutionary relationship between these sequences and various cellular immune pathways. At the most basic level, superinfection exclusion may be considered a prototypical virus-mediated immune system that has been described in both prokaryotes and eukaryotes. More complex immune mechanisms fully or partially derived from mobile genetic elements include CRISPR-Cas of prokaryotes and the RAG1/2 system of vertebrates, which provide immunological memory of foreign genetic elements and generate antibody and T cell receptor diversity, respectively. In this review, we summarize the current knowledge on the contribution of mobile genetic elements to the evolution of cellular immune pathways. A picture is emerging in which the various cellular immune systems originate from and are spread by viruses and transposable elements. Immune systems likely evolved from simple superinfection exclusion to highly complex defense strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.