Evidence map›Paper›PMID 30760990›Full record

ArticleFrontiers in human neuroscience2019

Modulatory Effects of Motor State During Paired Associative Stimulation on Motor Cortex Excitability and Motor Skill Learning.

Jacqueline A Palmer, Alice Halter, Whitney Gray, Steven L Wolf, Michael R Borich

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jacqueline A PalmerDepartment of Rehabilitation Medicine, Division of Physical Therapy, Emory University, Atlanta, GA, United States.
Alice HalterDepartment of Rehabilitation Medicine, Division of Physical Therapy, Emory University, Atlanta, GA, United States.
Whitney GrayDepartment of Rehabilitation Medicine, Division of Physical Therapy, Emory University, Atlanta, GA, United States.
Steven L WolfDepartment of Rehabilitation Medicine, Division of Physical Therapy, Emory University, Atlanta, GA, United States.
Michael R BorichDepartment of Rehabilitation Medicine, Division of Physical Therapy, Emory University, Atlanta, GA, United States.

Funding

MULTICENTER CAREER DEVELOPMENT PROGRAM FOR PHYSICAL AND OCCUPATIONAL THERAPYK12HD055931 · NICHD · WASHINGTON UNIVERSITY · PI HAYES, MARCIE HARRIS · 2007 to 2021
$12.7M
NINDS Stroke Trials Network - Regional Coordinating Stroke Centers (U10)U10NS086607 · NINDS · EMORY UNIVERSITY · PI FRANKEL, MICHAEL ROSS · 2013 to 2017
$1.7M
NICHD NIH HHS K12 HD055931NINDS NIH HHS U10 NS086607
6 · The paper itself

Abstract

Repeated pairing of electrical stimulation of a peripheral nerve with transcranial magnetic stimulation (TMS) over the primary motor cortex (M1) representation for a target muscle can induce neuroplastic adaptations in the human brain related to motor learning. The extent to which the motor state during this form of paired associative stimulation (PAS) influences the degree and mechanisms of neuroplasticity or motor learning is unclear. Here, we investigated the effect of volitional muscle contraction during PAS on: (1) measures of general corticomotor excitability and intracortical circuit excitability; and (2) motor performance and learning. We assessed measures of corticomotor excitability using TMS and motor skill performance during a serial reaction time task (SRTT) at baseline and at 0, 30, 60 min post-PAS. Participants completed a SRTT retention test 1 week following the first two PAS sessions. Following the PAS intervention where the hand muscle maintained an active muscle contraction (PAS

Indexed as

cortical excitabilitymotor cortexmotor learningpaired associative stimulationplasticitytranscranial magnetic stimulation

Identifiers

PMID30760990
PMCPMC6361855

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.