Evidence map›Paper›PMID 30760975›Full record

ArticleFrontiers in neuroscience2019

Serum Amyloid Alpha Is Downregulated in Peripheral Tissues of Parkinson's Disease Patients.

Lille Kurvits, Ene Reimann, Liis Kadastik-Eerme, Laura Truu, Külli Kingo, Triin Erm, Sulev Kõks, Pille Taba, Anu Planken

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Human serum proteomics reveals a molecular signature after one night of sleep deprivation.Sleep advances : a journal of the Sleep Research Society · 2024
    Article
  4. Article
  5. Review
  6. At the dawn of the transcriptomic medicine.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Lille KurvitsDepartment of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia.
Ene ReimannInstitute of Pathophysiology, University of Tartu, Tartu, Estonia.
Liis Kadastik-EermeDepartment of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia.
Laura TruuLaboratory of Bioenergetics, National Institute of Chemical Physics and Biophysics, Tallinn, Estonia.
Külli KingoDepartment of Dermatology, University of Tartu, Tartu, Estonia.
Triin ErmDepartment of Pathology, Tartu University Hospital, Tartu, Estonia.
Sulev KõksCentre for Comparative Genomics, Murdoch University, Perth, WA, Australia.
Pille TabaDepartment of Neurology and Neurosurgery, University of Tartu, Tartu, Estonia.
Anu PlankenOncology and Haematology Clinic, North-Estonian Medical Centre, Tallinn, Estonia.
University of Tartu · EENational Institute of Chemical Physics and Biophysics · EENorth Estonia Medical Centre · EETartu University Hospital · EEUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the changed levels of serum amyloid alpha, an immunologically active protein, in Parkinson's disease (PD) patients' peripheral tissues. We have previously shown that

Indexed as

intrinsically disordered protein (IDP)neurodegenarative diseaseParkinson’s disease (PD)serum amyloid A (SAA)skin biopsy

Identifiers

PMID30760975
PMCPMC6361740
OpenAlexW2912431583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.