ArticleNature2019
Sleep modulates haematopoiesis and protects against atherosclerosis.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 266 papers.
0numbers the graph read from it
0cells of the map it votes in
266citing papers in PubMed
27.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
266 citing papers in PubMed, 418 citations in OpenAlex.
- Comparative Effects of Two Acupuncture Protocols in the Management of Chronic Insomnia: A Randomized Controlled Trial.Nature and science of sleep · 2025Trial
- Impact of sleep restriction on biomarkers of thyroid function: Two pooled randomized trials.Sleep medicine · 2024Trial
- Trial
- Article
- Modeling the Exposome in Murine Cardiovascular Disease.JACC. Basic to translational science · 2026Review
- Gene regulatory network analysis identifies auranofin as an anti-atherosclerotic drug.Nature communications · 2026Article
- Inflammation and Immune Mechanisms in Atherosclerosis.Reviews in cardiovascular medicine · 2026Review
- Chronic intermittent hypoxia sustains the low-grade inflammatory memory of monocytes via activation of myelopoiesis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Cardiovascular risks and hazards associated with deep space exploration.Communications medicine · 2026Review
- Causal Bayesian network learning: application to the causal analysis of masticatory function and coronary heart disease in older adults.BMC medical informatics and decision making · 2026Article
- Translational applications of circadian research: connecting chronobiology to medicine.Npj biological timing and sleep · 2026Review
- Sleep regulates hepatic neutrophil trafficking by modulating uric acid metabolism via sympathetic nervous system activity.bioRxiv : the preprint server for biology · 2026Article
- Neighborhood socioeconomic deprivation and physical activity associate with extracellular vesicle size and cargo in a community-based cohort of women.Scientific reports · 2026Article
- Trained immunity: new paradigm in the immunological memory of cardiovascular disease.ImmunoHorizons · 2026Review
- Sleep and circadian rhythms in cardiovascular resilience: mechanisms, implications, and a Roadmap for research and interventions.Nature reviews. Cardiology · 2026Review
- Association of Sleep Duration With Intracranial Atherosclerosis and Cerebral Small Vessel Disease: A Mediation by Metabolic Factors.CNS neuroscience & therapeutics · 2026Observational
- Artery Tertiary Lymphoid Organs Establish Biological Platforms to Connect Atherosclerotic Plaques to the Brain.Current atherosclerosis reports · 2026Review
- Hepatic steatosis associates with leukopoietic activity and atherosclerotic inflammation: mechanistic insights into cardiovascular risk.Metabolism: clinical and experimental · 2026Article
- Targeting the heart-immune axis after myocardial infarction: from inflammation to immunomodulation.Frontiers in cardiovascular medicine · 2026Review
- Neuromodulation and Copper Chelation Reverse Sleep Fragmentation-Aggravated Myocardial Ischemia-Reperfusion Injury by Targeting NET-Induced Endothelial Cuproptosis.Research (Washington, D.C.) · 2026Article
206 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
23 authors at 7 institutions in 3 countries.
Cameron S McAlpineCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Máté G KissCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Sara RattikCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Shun HeCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Anne VassalliDepartment of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Colin ValetCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Atsushi AnzaiCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Christopher T ChanCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
John E MindurCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Florian KahlesCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Wolfram C PollerCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Vanessa FrodermannCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Ashley M FennCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Annemijn F GregoryCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Lennard HalleCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Yoshiko IwamotoCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Friedrich F HoyerCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Christoph J BinderDepartment of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Peter LibbyCardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Mehdi TaftiDepartment of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Thomas E ScammellDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Matthias NahrendorfCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Filip K SwirskiCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. fswirski@mgh.harvard.edu.
Massachusetts General Hospital · USCenter for Systems Biology · USHarvard University · USUniversity of Lausanne · CHAustrian Academy of Sciences · ATBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · US
Funding
Translational imaging and nanomedicine in inflammatory atherosclerosisP01HL131478 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Zahi A. Fayad · 2017 to 2026
$24.3MImaging organ system interfaces in ischemic heart diseaseR35HL139598 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS · 2018 to 2024
$6.9MMacrophages in homeostasis and cardiovascular diseaseR35HL135752 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SWIRSKI, FILIP K · 2017 to 2023
$5.4MMonocyte Heterogeneity in Experimental and Human AtherosclerosisR01HL095612 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI SWIRSKI, FILIP K · 2009 to 2016
$3.4MLifestyle effects on hematopoiesis and atherosclerosisR01HL128264 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS, SWIRSKI, FILIP K · 2015 to 2018
$3.3MNHLBI NIH HHS P01 HL131478NHLBI NIH HHS R01 HL095612NHLBI NIH HHS R01 HL128264NHLBI NIH HHS R35 HL135752NHLBI NIH HHS R35 HL139598
Abstract
Sleep is integral to life
Indexed as
AnimalsAntigens, LyAtherosclerosisBone Marrow CellsFemaleHematopoiesisHypothalamic Area, LateralMacrophage Colony-Stimulating FactorMaleMiceMonocytesMyelopoiesisNeutrophilsOrexin ReceptorsOrexinsSleepAntigens, LyCSF1 protein, mouseHcrt protein, mouseLy-6C antigen, mouseMacrophage Colony-Stimulating FactorOrexin ReceptorsOrexins
Identifiers
What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.