ArticleNature2019
Singlet molecular oxygen regulates vascular tone and blood pressure in inflammation.
Open access · bronzeAbstract read
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Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
8.6field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 113 citations in OpenAlex.
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- Monooxygenase Activity of Indoleamine 2,3-Dioxygenase.Journal of the American Chemical Society · 2026Article
- Vessels in Middle-Earth: meeting report from the 2025 Australasian Summit on Vascular Biology and Microcirculation.Vascular biology (Bristol, England) · 2026Article
- Is uric acid a true antioxidant? Identification of uric acid oxidation products and their biological effects.Redox report : communications in free radical research · 2025Review
- Sympathetic regulation of the host immune response to bacterial sepsis.Clinical science (London, England : 1979) · 2025Review
- Overcoming Photochemical Limitations in Covalent Organic Frameworks: Low-Energy Light Driven SelectiveAngewandte Chemie (International ed. in English) · 2025Article
- Fluorine-fluorine interaction-driven colorimetric sensor for PFOA-sensitive detection using F-functionalized Ce-UiO-66-NHMikrochimica acta · 2025Article
- LC/MS/MS detection of uric acid oxidation metabolites to evaluate reactive oxygen and nitrogen speciesJournal of clinical biochemistry and nutrition · 2025Article
- Effects of microbe-derived antioxidants on growth performance, hepatic oxidative stress, mitochondrial function and cell apoptosis in weaning piglets.Journal of animal science and biotechnology · 2024Article
- Plasmalogen oxidation induces the generation of excited molecules and electrophilic lipid species.PNAS nexus · 2024Article
- Retention of stress susceptibility in the mdx mouse model of Duchenne muscular dystrophy after PGC-1α overexpression or ablation of IDO1 or CD38.Human molecular genetics · 2024Article
- 5-Journal of clinical biochemistry and nutrition · 2024Article
- Transcranial photobiomodulation for brain diseases: review of animal and human studies including mechanisms and emerging trends.Neurophotonics · 2024Review
- A Review of the Evidence for Tryptophan and the Kynurenine Pathway as a Regulator of Stem Cell Niches in Health and Disease.International journal of tryptophan research : IJTR · 2024Review
- Colloidal Quantum Dots as an Emerging Vast Platform and Versatile Sensitizer for Singlet Molecular Oxygen Generation.ACS omega · 2023Review
- The Role of Oxidants in Percutaneous Coronary Intervention-Induced Endothelial Dysfunction: Can We Harness Redox Signaling to Improve Clinical Outcomes?Antioxidants & redox signaling · 2023Review
- Low-Level Laser Treatment Induces the Blood-Brain Barrier Opening and the Brain Drainage System Activation: Delivery of Liposomes into Mouse Glioblastoma.Pharmaceutics · 2023Article
- Brain Waste Removal System and Sleep: Photobiomodulation as an Innovative Strategy for Night Therapy of Brain Diseases.International journal of molecular sciences · 2023Review
- Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors.Journal of enzyme inhibition and medicinal chemistry · 2022Article
Corrections and comments
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Authors and funding
23 authors at 10 institutions in 6 countries.
Christopher P Stanley *Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Ghassan J Maghzal *Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Anita AyerVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Jihan TalibVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Andrew M GiltrapSchool of Chemistry, The University of Sydney, Sydney, New South Wales, Australia.
Sudhir ShenguleVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Kathryn WolhuterVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Yutang WangCentre for Vascular Research, School of Medical Sciences (Pathology), The University of Sydney, Sydney, New South Wales, Australia.
Preet ChadhaVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Cacang SuarnaVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Oleksandra PrysyazhnaDepartment of Cardiology, Cardiovascular Division, King's College London, London, UK.
Jenna ScotcherDepartment of Cardiology, Cardiovascular Division, King's College London, London, UK.
Louise L DunnVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia.
Fernanda M PradoDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Nghi NguyenMedicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Jephthah O OdibaMedicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Jonathan B BaellMedicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Johannes-Peter StaschCardiovascular Research, Bayer AG, Wuppertal, Germany.
Yorihiro YamamotoSchool of Bioscience and Biotechnology, Tokyo University of Technology, Tokyo, Japan.
Paolo Di MascioDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil.
Philip EatonDepartment of Cardiology, Cardiovascular Division, King's College London, London, UK.
Richard J PayneSchool of Chemistry, The University of Sydney, Sydney, New South Wales, Australia.
Roland StockerVictor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia. r.stocker@victorchang.edu.au.
Victor Chang Cardiac Research Institute · AUMonash University · AUUniversity of Sydney · AUKing's College London · GBSt Vincent's Clinic · AUUniversidade de São Paulo · BRUNSW Sydney · AUBayer (Germany) · DESt Thomas' Hospital · GBTokyo University of Technology · JP
Funding
Biotechnology and Biological Sciences Research Council BB/C503646/1British Heart Foundation FS/11/45/28859British Heart Foundation IG/16/2/32273British Heart Foundation PG/10/98/28655British Heart Foundation PG/13/13/30018British Heart Foundation PG/15/26/31373British Heart Foundation PG/17/44/33064British Heart Foundation RG/12/12/29872British Heart Foundation RG/17/16/33294Medical Research Council G0600785Medical Research Council G0700320Medical Research Council G1000458Medical Research Council MR/K003232/1Medical Research Council MR/L009684/1Medical Research Council MR/P023150/1Medical Research Council MR/P023150/2Medical Research Council MR/R01065X/1Medical Research Council MR/R01065X/2
Abstract
Singlet molecular oxygen (
Indexed as
AnimalsBlood PressureCell LineCyclic GMP-Dependent Protein Kinase Type ICysteineEnzyme ActivationFemaleHumansHydrogen PeroxideIndoleamine-Pyrrole 2,3,-DioxygenaseInflammationMaleOxidation-ReductionRatsSignal TransductionSinglet OxygenCyclic GMP-Dependent Protein Kinase Type ICysteineHydrogen PeroxideIDO1 protein, humanIndoleamine-Pyrrole 2,3,-DioxygenaseSinglet OxygenTryptophanVasodilator Agents
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.