ArticleScientific reports2019
Whole-genome-based phylogeny of Bacillus cytotoxicus reveals different clades within the species and provides clues on ecology and evolution.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Integrated Genomic and Phenotypic Analyses Reveal Convergent Resistance Patterns in Clinical Candida tropicalis Isolates.Mycoses · 2026Article
- Enumeration Comparison Study of BACARA® 2 and RAPID'B. cereus® Agars to Mannitol-Egg Yolk-Polymyxin (MYP) Agar for Detection of Bacillus cereus Group Strains.Journal of AOAC International · 2025Article
- Meat and meat products as potential sources of emerging MDR Bacillus cereus: groEL gene sequencing, toxigenic and antimicrobial resistance.BMC microbiology · 2024Article
- Retrospective surveillance of viableFrontiers in microbiology · 2023Article
- A Comparative Analysis of the Core Proteomes within and among theMicroorganisms · 2022Article
- Bacillus cytotoxicus-A potentially virulent food-associated microbe.Journal of applied microbiology · 2022Review
- New Insights into the Potential Cytotoxic Role ofToxins · 2021Article
- Environmental dissemination of pathogenic Listeria monocytogenes in flowing surface waters in Switzerland.Scientific reports · 2021Article
- Further Insights into the Toxicity ofToxins · 2021Article
- The Distribution of Several Genomic Virulence Determinants Does Not Corroborate the Established Serotyping Classification ofInternational journal of molecular sciences · 2021Article
- The Food Poisoning Toxins ofToxins · 2021Review
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- Whole Genome Sequence-Based Identification ofFrontiers in microbiology · 2021Article
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- Draft Genome Sequence of CH_213, a Highly Cytotoxic Bacillus cytotoxicus Strain Isolated from Mashed Potatoes.Microbiology resource announcements · 2020Article
- Bacillus subtilis EA-CB0575 genome reveals clues for plant growth promotion and potential for sustainable agriculture.Functional & integrative genomics · 2020Article
- Complete Genome Sequence of Bacillus cereus Strain PL1, Isolated from Soil in Japan.Microbiology resource announcements · 2020Article
- No Assembly Required: Using BTyper3 to Assess the Congruency of a Proposed Taxonomic Framework for theFrontiers in microbiology · 2020Article
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6 authors.
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Abstract
Bacillus cytotoxicus is a member of the Bacillus cereus group linked to fatal cases of diarrheal disease. Information on B. cytotoxicus is very limited; in particular comprehensive genomic data is lacking. Thus, we applied a genomic approach to characterize B. cytotoxicus and decipher its population structure. To this end, complete genomes of ten B. cytotoxicus were sequenced and compared to the four publicly available full B. cytotoxicus genomes and genomes of other B. cereus group members. Average nucleotide identity, core genome, and pan genome clustering resulted in clear distinction of B. cytotoxicus strains from other strains of the B. cereus group. Genomic content analyses showed that a hydroxyphenylalanine operon is present in B. cytotoxicus, but absent in all other members of the B. cereus group. It enables degradation of aromatic compounds to succinate and pyruvate and was likely acquired from another Bacillus species. It allows for utilization of tyrosine and might have given a B. cytotoxicus ancestor an evolutionary advantage resulting in species differentiation. Plasmid content showed that B. cytotoxicus is flexible in exchanging genes, allowing for quick adaptation to the environment. Genome-based phylogenetic analyses divided the B. cytotoxicus strains into four clades that also differed in virulence gene content.
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