Evidence map›Paper›PMID 30760609›Full record

ArticlemSphere2019

A CRISPR Interference Platform for Efficient Genetic Repression in

Lauren Wensing, Jehoshua Sharma, Deeva Uthayakumar, Yannic Proteau, Alejandro Chavez, Rebecca S Shapiro

Abstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. EditingBiomolecules · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Recent Advances in CRISPR-Cas Technologies for Synthetic Biology.Journal of microbiology (Seoul, Korea) · 2023
    Review
  19. Application of the Mutant Libraries forInternational journal of molecular sciences · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lauren Wensing *Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Jehoshua Sharma *Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Deeva UthayakumarDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Yannic ProteauDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Alejandro ChavezDepartment of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Rebecca S ShapiroDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada shapiror@uoguelph.ca.ORCID 0000-0002-7119-8865

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal pathogens are emerging as an important cause of human disease, and

Indexed as

CRISPR-Cas SystemsTranscription, GeneticCandida albicansCRISPR-Associated Protein 9Gene Expression Regulation, FungalGenetic EngineeringPromoter Regions, GeneticRNA, Guide, CRISPR-Cas SystemsCRISPR-Associated Protein 9RNA, Guide, CRISPR-Cas SystemsCandidaCandida albicansCRISPRCRISPRifungal geneticsgenetic regulationgenetic technology

Identifiers

PMID30760609
PMCPMC6374589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.