Evidence map›Paper›PMID 30760554›Full record

ArticleLife science alliance2019

Mucosa-associated microbiota drives pathogenic functions in IBD-derived intestinal iNKT cells.

Claudia Burrello, Gabriella Pellegrino, Maria Rita Giuffrè, Giulia Lovati, Ilaria Magagna, Alice Bertocchi, Fulvia Milena Cribiù, Francesca Boggio, Fiorenzo Botti, Elena Trombetta and 6 more

Abstract read
In one paragraph

Article in Life science alliance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Trial
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  6. Article
  7. Article
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  9. Review
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  11. Article
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  13. Development of αβ T Cells with Innate Functions.Advances in experimental medicine and biology · 2022
    Article
  14. Article
  15. Article
  16. Microorganisms · 2020
    Article
  17. Review
  18. Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Claudia BurrelloDepartment of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy.ORCID 0000-0003-2249-5588
Gabriella PellegrinoGastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Maria Rita GiuffrèGastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Giulia LovatiDepartment of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy.
Ilaria MagagnaDepartment of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy.
Alice BertocchiDepartment of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy.
Fulvia Milena CribiùPathology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Francesca BoggioPathology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Fiorenzo BottiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Elena TrombettaFlow Cytometry Service, Clinical Chemistry and Microbiology Laboratory Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Laura PorrettiFlow Cytometry Service, Clinical Chemistry and Microbiology Laboratory Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID 0000-0001-8100-4262
Antonio Di SabatinoFirst Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Maurizio VecchiGastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Maria RescignoDepartment of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy.
Flavio CaprioliGastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Federica FacciottiDepartment of Experimental Oncology, IEO, European Istitute of Oncology IRCCS, Milan, Italy Federica.facciotti@ieo.it.ORCID 0000-0002-2541-9428

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) pathogenesis has been linked to the aberrant activation of the Gut-associated lymphoid tissues against components of the intestinal microbiota. Although the contribution of CD4

Indexed as

Gastrointestinal MicrobiomeAdultAgedAged, 80 and overAnimalsCaco-2 CellsCD4 AntigensClone CellsCoculture TechniquesColitis, UlcerativeCrohn DiseaseCytokinesDextran SulfateDisease Models, AnimalFemaleHumansCD4 AntigensCytokinesDextran SulfateKLRB1 protein, humanNK Cell Lectin-Like Receptor Subfamily B

Identifiers

PMID30760554
PMCPMC6374994

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.