Evidence map›Paper›PMID 30760525›Full record

ArticleThe Journal of biological chemistry2019

The copper-sensing transcription factor Mac1, the histone deacetylase Hst1, and nicotinic acid regulate

Christol James Theoga Raj, Trevor Croft, Padmaja Venkatakrishnan, Benjamin Groth, Gagandeep Dhugga, Timothy Cater, Su-Ju Lin

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. NADCells · 2025
    Review
  4. Review
  5. Review
  6. Dysfunctional copper homeostasis inRedox biochemistry and chemistry · 2024
    Article
  7. Review
  8. The Histone Deacetylases Hst1 and Rpd3 Integrate De Novo NADInternational journal of molecular sciences · 2023
    Article
  9. Review
  10. Review
  11. NADFrontiers in molecular biosciences · 2021
    Review
  12. Article
  13. Review
  14. NADBiomolecules · 2020
    Review
  15. Article
  16. Cross-talk in NADCurrent genetics · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Christol James Theoga RajFrom the Department of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, California 95616.
Trevor CroftFrom the Department of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, California 95616.
Padmaja VenkatakrishnanFrom the Department of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, California 95616.
Benjamin GrothFrom the Department of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, California 95616.
Gagandeep DhuggaFrom the Department of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, California 95616.
Timothy CaterFrom the Department of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, California 95616.
Su-Ju LinFrom the Department of Microbiology and Molecular Genetics, College of Biological Sciences, University of California, Davis, California 95616 slin@ucdavis.edu.
University of California, Davis · US

Funding

Understanding the Regulation of NAD+Homeostasis and SignalingR01GM102297 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LIN, SU-JU · 2012 to 2019
$2.2M
NIGMS NIH HHS R01 GM102297
6 · The paper itself

Abstract

NADH (NAD

Indexed as

AnimalsCopperMiceNADNiacinNuclear ProteinsQuinolinic AcidSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSirtuin 2Transcription FactorsCopperHST1 protein, S cerevisiaeMAC1 protein, S cerevisiaeNADNiacinNuclear ProteinsQuinolinic AcidSaccharomyces cerevisiae ProteinsSirtuin 2Transcription Factorscell metabolismepigeneticsgene regulationhistone deacetylasemetabolic regulationmetal sensingNAD+ biosynthesisnicotinamide adenine dinucleotide (NAD)nicotinic acidyeast geneticsyeast metabolism

Identifiers

PMID30760525
PMCPMC6462523
OpenAlexW2913307067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.