Evidence map›Paper›PMID 30760520›Full record

ArticleCancer research2019

Transcriptomics Associates Molecular Features with

Sandi A Kwee, Maarit Tiirikainen, Miles M Sato, Jared D Acoba, Runmin Wei, Wei Jia, Loic Le Marchand, Linda L Wong

Open access · bronzeAbstract read
In one paragraph

Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Comparison ofCancer science · 2025
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  3. Review
  4. Review
  5. Review
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  7. Article
  8. Addition of [Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2020
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sandi A KweeHamamatsu/Queen's PET Imaging Center, The Queen's Medical Center, Honolulu, Hawaii. kwee@hawaii.edu.ORCID 0000-0002-4624-8787
Maarit TiirikainenCancer Biology Program, Clinical Sciences Program, and Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii.ORCID 0000-0002-8124-3818
Miles M SatoThe Queen's Medical Center, Queen's Cancer Center, Honolulu, Hawaii.
Jared D AcobaCancer Biology Program, Clinical Sciences Program, and Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii.ORCID 0000-0003-4145-8010
Runmin WeiCancer Biology Program, Clinical Sciences Program, and Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii.ORCID 0000-0001-7707-0160
Wei JiaCancer Biology Program, Clinical Sciences Program, and Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii.
Loic Le MarchandCancer Biology Program, Clinical Sciences Program, and Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii.
Linda L WongCancer Biology Program, Clinical Sciences Program, and Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, Hawaii.ORCID 0000-0003-3143-5384
University of Hawaiʻi at Mānoa · USQueen's Medical Center · US

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2M
RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI HEDGES, JERRIS ROBERT, MOKUAU, NOREEN · 2012 to 2018
$21.1M
Functional Genomics and Molecular Imaging of Liver Disease and CancerR01CA161209 · NCI · QUEEN'S MEDICAL CENTER · PI KWEE, SANDI ALEXANDER, OKIMOTO, GORDON SHOJI · 2011 to 2016
$2.2M
NCI NIH HHS P30 CA071789NCI NIH HHS R01 CA161209NIMHD NIH HHS U54 MD007584
6 · The paper itself

Abstract

Studies involving transcriptomics have revealed multiple molecular subtypes of hepatocellular carcinoma (HCC). Positron emission tomography/computed tomography (PET/CT) has also identified distinct molecular imaging subtypes, including those with increased and decreased choline metabolism as measured by the tissue uptake of the radiopharmaceutical

Indexed as

TranscriptomeAgedCarcinoma, HepatocellularCholineFemaleGene Expression ProfilingHumansLiver NeoplasmsMaleMiddle AgedPositron Emission Tomography Computed TomographySurvival AnalysisCholinefluorocholine

Identifiers

PMID30760520
PMCPMC6494445
OpenAlexW2914685299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.