Evidence map›Paper›PMID 30760250›Full record

ArticleBMC psychiatry2019

A stepped wedge cluster randomised trial of a cognitive remediation intervention in alcohol and other drug (AOD) residential treatment services.

Jamie Berry, Isabella Jacomb, Jo Lunn, Antoinette Sedwell, Anthony Shakeshaft, Peter J Kelly, Pooria Sarrami, Megan James, Skye Russell, Talia Nardo and 2 more

Abstract readClinical Trial Protocol
In one paragraph

Article in BMC psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jamie BerryMacquarie University, Balaclava Road, North Ryde, NSW, 2109, Australia.
Isabella JacombMacquarie University, Balaclava Road, North Ryde, NSW, 2109, Australia.
Jo LunnWe Help Ourselves, PO Box 1779, Rozelle, NSW, 2039, Australia.
Antoinette SedwellAgency for Clinical Innovation, Level 4, 67 Albert Ave, Chatswood, NSW, 2067, Australia.
Anthony ShakeshaftNational Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, 2052, Australia.
Peter J KellyIllawarra Health and Medical Research Institute and the School of Psychology, Faculty of Social Sciences, University of Wollongong, Building 41, Room 128, Wollongong, NSW, 2522, Australia.
Pooria SarramiAgency for Clinical Innovation, Level 4, 67 Albert Ave, Chatswood, NSW, 2067, Australia.
Megan JamesAgency for Clinical Innovation, Level 4, 67 Albert Ave, Chatswood, NSW, 2067, Australia.
Skye RussellAgency for Clinical Innovation, Level 4, 67 Albert Ave, Chatswood, NSW, 2067, Australia.
Talia NardoMacquarie University, Balaclava Road, North Ryde, NSW, 2109, Australia. Talia.nardo@hdr.mq.edu.au.ORCID 0000-0001-7881-2568
Daniel BarkerUniversity of Newcastle, University Drive, Callaghan, NSW, 2308, Australia.
Jennifer HolmesMinistry of Health NSW, 73 Miller St, North Sydney, NSW, 2060, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExecutive functioning impairment is common in substance use disorder and is a major risk factor for poor treatment outcomes, including treatment drop-out and relapse. Cognitive remediation interventions seek to improve executive functioning and offer a promising approach to increase the efficacy of alcohol and other drug (AOD) treatments and improve long-term therapeutic outcomes. This protocol describes a study funded by the NSW Agency for Clinical Innovation that assesses the effectiveness of delivering a six-week group-based intervention of cognitive remediation in an ecologically valid sample of people attending residential AOD treatment services. We primarily aim to investigate whether cognitive remediation will be effective in improving executive functioning and treatment retention rates. We will also evaluate if cognitive remediation may reduce long-term AOD use and rates of health service utilisation, as well as improve personal goal attainment, quality of life, and client satisfaction with treatment. In addition, the study will involve an economic analysis of the cost of delivering cognitive remediation. METHODS/

designThe study uses a stepped wedge cluster randomised design, where randomisation will occur at the cluster level. Participants will be recruited from ten residential AOD treatment services provided by the non-government sector. The intervention will be delivered in 12 one-hour group-based sessions over a period of six weeks. All participants who are expected to receive treatment for the duration of the six-week intervention will be asked to participate in the study. The clusters of participants who are randomly assigned to the treatment condition will complete cognitive remediation in addition to treatment as usual (TAU). Primary and secondary outcome assessments will be conducted at pre-cognitive remediation/TAU phase, post-cognitive remediation/TAU phase, two-month follow-up, four-month follow-up, six-month follow-up, and eight-month follow-up intervals. DISCUSSION: This study will provide comprehensive data on the effect of delivering a cognitive remediation intervention within residential AOD treatment services. If shown to be effective, cognitive remediation may be incorporated as an adjunctive intervention in current treatment programs.

trial registrationAustralian and New Zealand Clinical Trials Register (ANZCTR): ACTRN12618001190291 . Prospectively registered 17th July 2018.

Indexed as

Executive FunctionAustraliaCognitive RemediationHumansMalePatient SatisfactionQuality of LifeRandomized Controlled Trials as TopicResidential TreatmentRisk FactorsSubstance-Related DisordersTreatment OutcomeYoung AdultAlcohol and drugCognitive rehabilitationCognitive remediationExecutive functionGoal settingTreatment retention

Identifiers

PMID30760250
PMCPMC6372999

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.