Evidence map›Paper›PMID 30760087›Full record

ArticleGut microbes2019

Compositional changes to the ileal microbiome precede the onset of spontaneous ileitis in SHIP deficient mice.

Peter Allan Dobranowski, Chris Tang, Jean Philippe Sauvé, Susan Christine Menzies, Laura May Sly

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 72 citations in OpenAlex.

  1. Gut microbes · 2026
    Article
  2. Article
  3. Role of Innate Oral Immunity and the Salivary Fluid in Inflammatory Bowel Disease.Cellular and molecular gastroenterology and hepatology · 2026
    Article
  4. Frontiers in microbiology · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Environmental and inflammatory factors influencing concurrent gut and lung inflammation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  11. Nutrients · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Novel microbiotaFrontiers in microbiology · 2024
    Article
  17. A Cardiolipin fromJournal of the American Chemical Society · 2023
    Article
  18. Article
  19. Effects ofFood science and biotechnology · 2023
    Article
  20. Biometabolites ofNutrients · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Peter Allan DobranowskiUniversity of British Columbia.ORCID 0000-0003-4613-8737
Chris TangUniversity of British Columbia.
Jean Philippe SauvéUniversity of British Columbia.
Susan Christine MenziesUniversity of British Columbia.
Laura May SlyUniversity of British Columbia.
University of British Columbia · CA

Funding

CIHR MOP-133607
6 · The paper itself

Abstract

Inflammatory bowel disease, encompassing both ulcerative colitis and Crohn's disease, is characterized by chronic, relapsing-remitting gastrointestinal inflammation of unknown etiology. SHIP deficient mice develop fully penetrant, spontaneous ileitis at 6 weeks of age, and thus offer a tractable model of Crohn's disease-like inflammation. Since disruptions to the microbiome are implicated in the pathogenesis of Crohn's disease, we conducted a 16S rRNA gene survey of the ileum, cecum, colon, and stool contents of SHIP

Indexed as

Gastrointestinal MicrobiomeAnimalsBacteriaCecumCrohn DiseaseDisease Models, AnimalFecesIleitisIleumMiceMice, Inbred C57BLMice, KnockoutPhosphatidylinositol-3,4,5-Trisphosphate 5-PhosphatasesRNA, Ribosomal, 16SInpp5d protein, mousePhosphatidylinositol-3,4,5-Trisphosphate 5-PhosphatasesRNA, Ribosomal, 16SCrohn’s diseaseileitisintestinal inflammationmicrobiomeSHIP

Identifiers

PMID30760087
PMCPMC6748580
OpenAlexW2912498165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.