Evidence map›Paper›PMID 30759960›Full record

ArticleJournal of clinical research in pediatric endocrinology2019

Associations Between Serum Uric Acid Concentrations and Cardiometabolic Risk and Renal Injury in Obese and Overweight Children

Deniz Özalp Kızılay, Semra Şen, Betül Ersoy

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

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  14. Serum Uric Acid Levels and Metabolic Indices in an Obese Population: A Cross-Sectional Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Deniz Özalp KızılayÇiğli State Training Hospital, Clinic of Pediatrics, Division of Pediatric Endocrinology, İzmir, TurkeyORCID 0000-0003-4529-4404
Semra ŞenManisa Celal Bayar University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Infectious Disease, Manisa, TurkeyORCID 0000-0002-9920-0269
Betül ErsoyManisa Celal Bayar University Faculty of Medicine, Department of Pediatrics, Division of Pediatric Endocrinology and Metabolism, Manisa, TurkeyORCID 0000-0003-1696-8406
Manisa Celal Bayar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to assess the association between serum uric acid concentration (SUAC) and the parameters of the metabolic syndrome (MetS) and insulin resistance (IR). The secondary aim was to evaluate whether hyperuricemia is associated with renal injury and cardiovascular risk in obese (OB) and overweight (OW) children. Methods: The subjects of this study consisted of OB/OW children and adolescents (ages: 8-18 years). Sex and age specific serum uric acid (SUA) olarak değiştirilecek percentiles were used and a SUA >75 Results: There were 128 participants; 52 (40%) had elevated (SUA >75 Conclusion: In OB/OW children frequency of MetS, IR and dislipidemia increases with increased SUAC, a finding independent of age, puberty, gender and body mass index. Patients meeting all of the MetS criteria had the highest SUAC. These results demonstrate that the association between UA and metabolic and cardiovascular risk factors can be detected early in childhood. Thus, we recommend monitoring SUAC in OB children and we believe that prevention of SUAC elevation in early life has a potential protective effect on metabolic impairment and subsequent comorbidities.

Indexed as

AdolescentBiomarkersBody Mass IndexCardiovascular DiseasesChildFemaleFollow-Up StudiesHumansHyperuricemiaKidney DiseasesMaleMetabolic SyndromeObesityOverweightPrognosisRetrospective StudiesBiomarkersUric Acidcardiovascular riskchildinsulin resistancemetabolic syndromeobesityrenal injurySerum uric acid concentration

Identifiers

PMID30759960
PMCPMC6745466
OpenAlexW2972142781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.