Evidence map›Paper›PMID 30759793›Full record

ArticleMedicina (Kaunas, Lithuania)2019

Lung Ultrasound B-lines Occurrence in Relation to Left Ventricular Function and Hydration Status in Hemodialysis Patients.

Agnieszka Pardała, Mariusz Lupa, Jerzy Chudek, Aureliusz Kolonko

Open access · goldAbstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Recommendations for Lung Ultrasound in Internal Medicine.Diagnostics (Basel, Switzerland) · 2020
    Guideline
  2. Observational
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Agnieszka PardałaDialysis Centre, Fresenius Nephrocare, 34-600 Limanowa, Poland. agnieszka.pardala@fmc-ag.com.
Mariusz LupaDepartment of Internal Medicine, District Hospital, 34-600 Limanowa, Poland. mariuszlupa@poczta.onet.pl.
Jerzy ChudekDepartment of Internal Medicine and Oncological Chemotherapy, Medical University of Silesia, 40-027 Katowice, Poland. chj@poczta.fm.ORCID 0000-0002-6367-7794
Aureliusz KolonkoDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, 40-027 Katowice, Poland. uryniusz@wp.pl.ORCID 0000-0002-9647-1872
Medical University of Silesia · PLInstar (Poland) · PL

Funding

Śląski Uniwersytet Medyczny KNW-1-077/N/7/K
6 · The paper itself

Abstract

BACKGROUND AND

objectiveReliable assessment of the fluid status in hemodialysis (HD) patients is often difficult. A lung ultrasound with an assessment of the B-lines ("lung comets" (LCs)) number is a novel hydration status measure. However, the occurrence of left ventricular dysfunction may have a significant effect on pulmonary congestion and further modulate the LC number. The aim of this study was to analyze to what extent left ventricular dysfunction, pulmonary hypertension, and hypervolemia affect the occurrence of LC in a cohort of prevalent HD patients. MATERIAL AND

methodsThis cross-sectional study included 108 assessments performed in 54 patients who attended thrice weekly outpatient HD. Each patient's fluid status was evaluated twice, prior to HD sessions, using echocardiography, LC number assessment, measurement of inferior vena cava (IVC) diameters, and bioelectric impedance analysis (BIA). Patients were stratified into three subgroups according to their LC number.

resultsThere were 76 separate assessments with mild (<14), 16 with moderate (14⁻30), and 16 with severe (>30) LC occurrence. There was a negative correlation between the LC number and left ventricular ejection fraction (LVEF), and positive correlations between the LC number and mitral gradient, and the left and right atrium area and volume, but not with the BIA-derived relative fluid overload. Multivariate linear regression analysis revealed that the LC number was proportionally related to the mitral gradient (β = 0.407 (0.247⁻0.567), p < 0.001) and IVC max diameter (β = 0.219 (0.060⁻0.378), p < 0.01), and was inversely related to LVEF (β = -0.431 (-0.580 to -0.282), p < 0.001).

conclusionsThe number of LCs appears to reflect both overhydration and left ventricular dysfunction in our HD patients cohort. Therefore, heart failure must be considered as an important factor limiting the usefulness of LCs number assessment in this population.

Indexed as

Organism Hydration StatusAgedCarotid Artery, CommonCohort StudiesCross-Sectional StudiesEchocardiographyElectric ImpedanceExtravascular Lung WaterFemaleHumansHypertension, PulmonaryLinear ModelsLungMaleMiddle AgedRenal Dialysisbioimpedance analysischronic kidney diseaseechocardiographyleft ventricular ejection fractionlung cometslung ultrasoundoverhydration

Identifiers

PMID30759793
PMCPMC6410033
OpenAlexW2301516922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.