Evidence map›Paper›PMID 30759348›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Functional definition of NrtR, a remnant regulator of NAD

Qingjing Wang, Bachar H Hassan, Ningjie Lou, Justin Merritt, Youjun Feng

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Regulation of NADPathogens (Basel, Switzerland) · 2025
    Article
  4. Characterization of the Nicotinamide Adenine Dinucleotide Biosynthesis Pathway and Regulatory Mechanisms in Streptococcus mutans.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Functional definition of NrtR, a remnant regulator of NADFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Qingjing WangDepartment of Pathogen Biology and Microbiology, Department of General Intensive Care Unit of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Bachar H HassanStony Brook Cancer Center, Stony Brook University, Stony Brook, New York, USA; and.
Ningjie LouDepartment of Pathogen Biology and Microbiology, Department of General Intensive Care Unit of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Justin MerrittDepartment of Restorative Dentistry, Oregon Health and Science University, Portland, Oregon, USA.
Youjun FengDepartment of Pathogen Biology and Microbiology, Department of General Intensive Care Unit of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Second Affiliated Hospital of Zhejiang University · CNOregon Health & Science University · USStony Brook University · US

Funding

Advancing studies of polymicrobial diseases via streptococcal geneticsR35DE028252 · NIDCR · OREGON HEALTH & SCIENCE UNIVERSITY · PI MERRITT, JUSTIN · 2018 to 2025
$7.8M
The IrvA-Dependent Pathway: A Link Between Stress Adaptation and VirulenceR01DE018893 · NIDCR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI MERRITT, JUSTIN · 2009 to 2018
$3.0M
The LytTR Regulatory Systems of Streptococcus mutansR01DE022083 · NIDCR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI MERRITT, JUSTIN · 2013 to 2016
$1.5M
NIDCR NIH HHS R01 DE018893NIDCR NIH HHS R01 DE022083NIDCR NIH HHS R35 DE028252
6 · The paper itself

Abstract

NAD

Indexed as

HomeostasisAnimalsBacterial ProteinsBiofilmsMiceNADNudix HydrolasesOperonProtein DomainsPyrophosphatasesStreptococcus suisTranscription FactorsVirulenceBacterial ProteinsNADNudix HydrolasesPyrophosphatasesTranscription FactorsADP-riboseNAD salvageNudix-related transcriptional regulatorSS2virulence

Identifiers

PMID30759348
PMCPMC8793812
OpenAlexW2911829473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.