ArticleJournal of the American Chemical Society2019
Catalytic Strategy for Regioselective Arylethylamine Synthesis.
Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
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- Regiodivergent α- and β-Functionalization of SaturatedJournal of the American Chemical Society · 2025Article
- Synergistic Photoenzymatic Anti-Markovnikov Hydroarylation of Olefins via Heteroaryl Radical Intermediates.Journal of the American Chemical Society · 2025Article
- Photocatalytic 1,3-difluoroalkylcarboxylation of alkenes by triple kinetic-controlled radical self-ordering.Chemical science · 2025Article
- A General Amino-(Hetero)arylation of Simple Olefins with (Hetero)aryl Sulfonamides Enabled by anACS catalysis · 2025Article
- Merging SOMO activation with transition metal catalysis: Deoxygenative functionalization of amides to β-aryl amines.Science advances · 2025Article
- Light-assisted functionalization of aryl radicals towards metal-free cross-coupling.Nature reviews. Chemistry · 2025Review
- Visible-light-driven alkene dicarboxylation with formate and COChemical science · 2024Article
- A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides.Nature chemistry · 2024Article
- Photoinduced Copper-Catalyzed Late-Stage Azidoarylation of Alkenes via Arylthianthrenium Salts.Journal of the American Chemical Society · 2023Article
- Photocatalytic Alkylation of C(spAngewandte Chemie (International ed. in English) · 2023Article
- Meerwein-type Bromoarylation with Arylthianthrenium Salts.Angewandte Chemie (International ed. in English) · 2022Article
- Effects of the Chalcogenide Identity inChemCatChem · 2022Article
- Visible-Light Photocatalytic Reduction of Aryl Halides as a Source of Aryl Radicals.Molecules (Basel, Switzerland) · 2022Review
- Photochemical Synthesis of the Bioactive Fragment of Salbutamol and Derivatives in a Self-Optimizing Flow Chemistry Platform.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Mechanism of Visible Light-Mediated Alkene Aminoarylation with Arylsulfonylacetamides.ACS catalysis · 2022Article
- Catalytic intramolecular aminoarylation of unactivated alkenes with aryl sulfonamides.Chemical science · 2022Article
- Photo-induced catalytic halopyridylation of alkenes.Nature communications · 2021Article
- Article
- An Efficient Synthesis of 3-Alkylpyridine Alkaloids Enables Their Biological Evaluation.ChemMedChem · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
A mild, modular, and practical catalytic system for the synthesis of the highly privileged phenethylamine pharmacophore is reported. Using a unique combination of organic catalysts to promote the transfer of electrons and hydrogen atoms, this system performs direct hydroarylation of vinyl amine derivatives with a wide range of aryl halides (including aryl chlorides). This general and highly chemoselective protocol delivers a broad range of arylethylamine products with complete regiocontrol. The utility of this process is highlighted by its scalability and the modular synthesis of an array of bioactive small molecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.