Evidence map›Paper›PMID 30759321›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2019

Parkinson's disease: Is it a consequence of human brain evolution?

Nico J Diederich, D James Surmeier, Toshiki Uchihara, Sten Grillner, Christopher G Goetz

Abstract read
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Movement disorders: a brief overview from an evolutionary perspective.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  4. Article
  5. Article
  6. Evolutionary innovations in the primate dopaminergic system.Current opinion in genetics & development · 2024
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Neuromelanin in Parkinson's Disease: Tyrosine Hydroxylase and Tyrosinase.International journal of molecular sciences · 2022
    Review
  17. Brain Metabolic Alterations in Alzheimer's Disease.International journal of molecular sciences · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nico J DiederichDepartment of Neurosciences, Centre Hospitalier de Luxembourg, Luxembourg City, Luxembourg.
D James SurmeierDepartment of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Toshiki UchiharaNeurology Clinic with Neuromorphomics Laboratory, Nitobe Memorial Nakano General Hospital, Tokyo, Japan.
Sten GrillnerDepartment of Neuroscience, Karolinska Institut, Stockholm, Sweden.
Christopher G GoetzDepartment of Neurological Sciences, Rush University, Chicago, Illinois, USA.

Funding

SYNAPTIC CONTROLOF PALLIDAL ACTIVITYP50NS047085 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KRAINC, DIMITRI · 2003 to 2018
$19.2M
NINDS NIH HHS P50 NS047085
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biological EvolutionBrainHumansParkinson Disease

Identifiers

PMID30759321
PMCPMC6593760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.