Evidence map›Paper›PMID 30759251›Full record

ArticleThe Journal of clinical endocrinology and metabolism2019

Associations of Outdoor Temperature, Bright Sunlight, and Cardiometabolic Traits in Two European Population-Based Cohorts.

Raymond Noordam, Ashna Ramkisoensing, Nellie Y Loh, Matt J Neville, Frits R Rosendaal, Ko Willems van Dijk, Diana van Heemst, Fredrik Karpe, Constantinos Christodoulides, Sander Kooijman

Open access · greenAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  4. Beneficial health effects of ultraviolet radiation: expert review and conference report.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Higher ambient temperature is associated with worsening of HbA1c levels in a Saudi population.International journal of clinical and experimental pathology · 2021
    Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Raymond NoordamDepartment of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands.
Ashna RamkisoensingDepartment of Molecular Cell Biology, Division of Neurophysiology, Leiden University Medical Center, Leiden, Netherlands.
Nellie Y LohRadcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom.
Matt J NevilleRadcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom.
Frits R RosendaalDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands.
Ko Willems van DijkDepartment of Human Genetics, Leiden University Medical Center, Leiden, Netherlands.
Diana van HeemstDepartment of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands.
Fredrik KarpeRadcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom.
Constantinos ChristodoulidesRadcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom.
Sander KooijmanRadcliffe Department of Medicine, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford, United Kingdom.
Leiden University Medical Center · NLNational Institute for Health Research · GBUniversity of Oxford · GB

Funding

British Heart Foundation FS/16/45/32359British Heart Foundation RG/17/1/32663
6 · The paper itself

Abstract

contextSeasonal variation in cold and light exposure may influence metabolic health.

objectiveWe assessed the associations of bright sunlight and outdoor temperature with measures of glucose and lipid metabolism in two populations of middle-aged European subjects.

designCross-sectional study.

settingTwo population-based European cohorts.

participantsMiddle-aged nondiabetic subjects from the Oxford Biobank (OBB; N = 4327; mean age, 41.4 years) and the Netherlands Epidemiology of Obesity (NEO) study (N = 5899; mean age, 55.6 years).

interventionsData on outdoor bright sunlight and temperature collected from local weather stations.

main outcome measuresInsulin resistance and fasting lipid levels. Multivariable regression analyses were adjusted for age, sex, percentage body fat, season, and either outdoor temperature or bright sunlight.

resultsIn the OBB cohort, increased bright sunlight exposure was associated with lower fasting insulin [-1.27% (95% CI, -2.09 to -0.47%) per extra hour of bright sunlight], lower homeostatic model assessment for insulin resistance (-1.36%; 95% CI, -2.23 to -0.50), lower homeostatic model assessment for β-cell function (-0.80%; 95% CI, -1.31 to -0.30), and lower triglyceride (-1.28%; 95% CI, -2.07 to -0.50) levels. In the NEO cohort generally unidirectional but weaker associations were observed. No associations between outdoor temperature and measures of glucose or lipid metabolism were detected following adjustment for bright sunlight.

conclusionsBright sunlight, but not outdoor temperature, might be associated with increased insulin sensitivity and lower triglyceride levels.

Indexed as

Insulin ResistanceSunlightTemperatureAdipose TissueAdultBlood GlucoseCholesterol, HDLCholesterol, LDLCross-Sectional StudiesEnglandFemaleHumansInsulinMaleMiddle AgedMultivariate AnalysisBlood GlucoseCholesterol, HDLCholesterol, LDLInsulinTriglycerides

Identifiers

PMID30759251
PMCPMC6543772
OpenAlexW2914498933

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.