Evidence map›Paper›PMID 30759173›Full record

ArticlePloS one2019

The costs of negative affect attributable to alcohol consumption in later life: A within-between random longitudinal econometric model using UK Biobank.

Chenlu Li, Simon C Moore, Jesse Smith, Sarah Bauermeister, John Gallacher

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chenlu LiDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.
Simon C MooreCrime and Security Research Institute, Friary House, Greyfriars Road, Cardiff, United Kingdom.ORCID 0000-0001-5495-4705
Jesse SmithCentre for the Development and Evaluation of Complex Interventions for Public Health Improvement, School of Social Sciences, Cardiff University, Cardiff, United Kingdom.ORCID 0000-0001-7375-2463
Sarah BauermeisterDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.
John GallacherDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom.ORCID 0000-0002-2394-5299

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

aimsResearch demonstrates a negative relationship between alcohol use and affect, but the value of deprecation is unknown and thus cannot be included in estimates of the cost of alcohol to society. This paper aims to examine this relationship and develop econometric techniques to value the loss in affect attributable to alcohol consumption.

methodsCross-sectional (n = 129,437) and longitudinal (n = 11,352) analyses of alcohol consumers in UK Biobank data were undertaken, with depression and neuroticism as proxies of negative affect. The cross-sectional relationship between household income, negative affect and alcohol consumption were analysed using regression models, controlling for confounding variables, and using within-between random models that are robust to unobserved heterogeneity. The differential in household income required to offset alcohol's detriment to affect was derived.

resultsA consistent relationship between depression and alcohol consumption (β = 0.001, z = 7.64) and neuroticism and alcohol consumption (β = 0.001, z = 9.24) was observed in cross-sectional analyses, replicated in within-between models (depression β = 0.001, z = 2.32; neuroticism β = 0.001, z = 2.33). Significant associations were found between household income and depression (cross sectional β = -0.157, z = -23.86, within-between β = -0.146, z = -9.51) and household income and neuroticism (cross sectional β = -0.166, z = -32.02, within-between β = -0.158, z = -7.44). The value of reducing alcohol consumption by one gram/day was pooled and estimated to be £209.06 (95% CI £171.84 to £246.27).

conclusionsThere was a robust relationship between alcohol consumption and negative affect. Econometric methods can value the intangible effects of alcohol use and may, therefore, facilitate the fiscal determination of benefit.

Indexed as

NeuroticismAdultAffectAgedAlcohol DrinkingBiological Specimen BanksCross-Sectional StudiesDepressionFemaleHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedModels, EconometricSocial Class

Identifiers

PMID30759173
PMCPMC6373896

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.