Evidence map›Paper›PMID 30759094›Full record

ArticlePloS one2019

An attention based deep learning model of clinical events in the intensive care unit.

Deepak A Kaji, John R Zech, Jun S Kim, Samuel K Cho, Neha S Dangayach, Anthony B Costa, Eric K Oermann

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  16. Body Surface Potential Mapping: A Perspective on High-Density Cutaneous Electrophysiology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deepak A KajiIcahn School of Medicine at Mount Sinai, Department of Orthopaedics, New York, NY, United States of America.ORCID 0000-0002-0470-3219
John R ZechIcahn School of Medicine at Mount Sinai, Department of Orthopaedics, New York, NY, United States of America.ORCID 0000-0003-1317-8951
Jun S KimIcahn School of Medicine at Mount Sinai, Department of Orthopaedics, New York, NY, United States of America.
Samuel K ChoIcahn School of Medicine at Mount Sinai, Department of Orthopaedics, New York, NY, United States of America.
Neha S DangayachIcahn School of Medicine at Mount Sinai, Department of Neurological Surgery, New York, NY, United States of America.
Anthony B CostaIcahn School of Medicine at Mount Sinai, Department of Neurological Surgery, New York, NY, United States of America.
Eric K OermannIcahn School of Medicine at Mount Sinai, Department of Neurological Surgery, New York, NY, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study trained long short-term memory (LSTM) recurrent neural networks (RNNs) incorporating an attention mechanism to predict daily sepsis, myocardial infarction (MI), and vancomycin antibiotic administration over two week patient ICU courses in the MIMIC-III dataset. These models achieved next-day predictive AUC of 0.876 for sepsis, 0.823 for MI, and 0.833 for vancomycin administration. Attention maps built from these models highlighted those times when input variables most influenced predictions and could provide a degree of interpretability to clinicians. These models appeared to attend to variables that were proxies for clinician decision-making, demonstrating a challenge of using flexible deep learning approaches trained with EHR data to build clinical decision support. While continued development and refinement is needed, we believe that such models could one day prove useful in reducing information overload for ICU physicians by providing needed clinical decision support for a variety of clinically important tasks.

Indexed as

Clinical Decision-MakingDeep LearningDiagnosis, Computer-AssistedIntensive Care UnitsModels, BiologicalAnti-Bacterial AgentsHumansMyocardial InfarctionRetrospective StudiesSepsisVancomycinAnti-Bacterial AgentsVancomycin

Identifiers

PMID30759094
PMCPMC6373907

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.