ArticlePLoS neglected tropical diseases2019
Potential for sylvatic and urban Aedes mosquitoes from Senegal to transmit the new emerging dengue serotypes 1, 3 and 4 in West Africa.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Building resilience against the growing threat of arboviruses II: a scoping review of Aedes vector competence, larval and adult bionomics and species distribution in Africa.Parasites & vectors · 2026Review
- Seroprevalence of dengue virus antibodies among multiple species of non-human primates in Senegal suggests that sylvatic dengue virus is maintained in non-primate reservoirs in this region.PLoS neglected tropical diseases · 2026Article
- Infectivity and Dissemination of Dengue Virus-1 in DifferentTropical medicine and infectious disease · 2025Article
- Article
- Nutritional stress compromises mosquito fitness and antiviral immunity, while enhancing dengue virus infection susceptibility.Communications biology · 2023Article
- Insecticide resistance status of Aedes aegypti in southern and northern Ghana.Parasites & vectors · 2023Article
- Analysis of a Dengue Virus Outbreak in Rosso, Senegal 2021.Tropical medicine and infectious disease · 2022Article
- Dengue vectors in Africa: A review.Heliyon · 2022Article
- Zika virus and temperature modulate Elizabethkingia anophelis in Aedes albopictus.Parasites & vectors · 2021Article
- Emergence of dengue virus serotype 2 in Mauritania and molecular characterization of its circulation in West Africa.PLoS neglected tropical diseases · 2021Article
- Genomic investigation of a dengue virus outbreak in Thiès, Senegal, in 2018.Scientific reports · 2021Observational
- Insecticide resistance status and mechanisms in Aedes aegypti populations from Senegal.PLoS neglected tropical diseases · 2021Article
- Genomic investigation of atypical malaria cases in Kanel, northern Senegal.Malaria journal · 2021Article
- Probability of consolidation constrains novel serotype emergence in dengue fever virus.PloS one · 2021Article
- Evaluating the competence of the primary vector, Culex tritaeniorhynchus, and the invasive mosquito species, Aedes japonicus japonicus, in transmitting three Japanese encephalitis virus genotypes.PLoS neglected tropical diseases · 2020Article
- First confirmed occurrence of the yellow fever virus and dengue virus vector Aedes (Stegomyia) luteocephalus (Newstead, 1907) in Mozambique.Parasites & vectors · 2020Article
- Vector competence of Aedes aegypti from New Caledonia for the four recent circulating dengue virus serotypes.PLoS neglected tropical diseases · 2020Article
- Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal.Emerging microbes & infections · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Dengue fever (DEN) is the most common arboviral disease in the world and dengue virus (DENV) causes 390 million annual infections around the world, of which 240 million are inapparent and 96 million are symptomatic. During the past decade a changing epidemiological pattern has been observed in Africa, with DEN outbreaks reported in all regions. In Senegal, all DENV serotypes have been reported. These important changes in the epidemiological profile of DEN are occurring in a context where there is no qualified vaccine against DEN. Further there is significant gap of knowledge on the vector bionomics and transmission dynamics in the African region to effectively prevent and control epidemics. Except for DENV-2, few studies have been performed with serotypes 1, 3, and 4, so this study was undertaken to fill out this gap. We assessed the vector competence of Aedes (Diceromyia) furcifer, Ae. (Diceromyia) taylori, Ae. (Stegomyia) luteocephalus, sylvatic and urban Ae. (Stegomyia) aegypti populations from Senegal for DENV-1, DENV-3 and DENV-4 using experimental oral infection. Whole bodies and wings/legs were tested for DENV presence by cell culture assays and saliva samples were tested by real time RT-PCR to estimate infection, disseminated infection and transmission rates. Our results revealed a low capacity of sylvatic and urban Aedes mosquitoes from Senegal to transmit DENV-1, DENV-3 and DENV-4 and an impact of infection on their mortality. The highest potential transmission rate was 20% despite the high susceptibility and disseminated infection rates up to 93.7% for the 3 Ae. aegypti populations tested, and 84.6% for the sylvatic vectors Ae. furcifer, Ae. taylori and Ae. luteocephalus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.