ReviewHead and neck pathology2019
Thyroid Gland Solitary Fibrous Tumor: Report of 3 Cases and a Comprehensive Review of the Literature.
Review in Head and neck pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Glomangiosarcoma-like Anaplastic Transformation in Papillary Thyroid Carcinoma: A Novel Form of Heterologous Differentiation and a Systematic Review of Heterologous Element Prevalence.Endocrine pathology · 2023Pooled it
- Review
- Solitary fibrous tumor: an updated review.Journal of pathology and translational medicine · 2026Article
- A schwannoma look-alike: solitary fibrous tumor of the cauda equina. Illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Solitary fibrous tumor of the chest wall.Indian journal of thoracic and cardiovascular surgery · 2025Article
- Synchronous occurrence of papillary thyroid carcinoma and solitary fibrous tumor of the thyroid: a case report.Journal of medical case reports · 2024Article
- Unveiling the Rarity: A Case Report on Solitary Fibrous Tumor of the Thyroid Gland.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Review
- Imaging diagnosis analysis and literature review of intrapulmonary solitary fibrous tumor.Quantitative imaging in medicine and surgery · 2023Article
- Primary Mesenchymal Tumors of the Thyroid Gland: A Modern Retrospective Cohort Including the First Case of TFE3-Translocated Malignant Perivascular Epithelioid Cell Tumor (PEComa).Head and neck pathology · 2022Article
- Magnetic resonance imaging features of a solitary fibrous tumor of the vulva: a case report.The Journal of international medical research · 2022Article
- Solitary Fibrous Tumors of the Chest: An Analysis of Fifty Patients.Frontiers in oncology · 2021Review
- Two case reports of rare diseases occurring in rare parts: splenic vein solitary fibrous tumor and liver solitary fibrous tumor.AME case reports · 2021Article
- Primary solitary fibrous tumor of the thyroid gland: A review starting from a case report.Archive of clinical cases · 2021Review
- Comprehensive guidance on the diagnosis and management of primary mesenchymal tumours of the thyroid gland.The Lancet. Oncology · 2020Review
- Papillary thyroid carcinoma with prominent myofibroblastic stromal component: clinicopathologic, immunohistochemical and next-generation sequencing study of seven cases.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020Article
- Extrapleural solitary fibrous tumor of the thyroid gland: A case report and review of literature.World journal of clinical cases · 2020Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solitary fibrous tumors of the thyroid gland are exceptionally rare. In order to further characterize the clinical and pathologic features of solitary fibrous tumor arising at this anatomic site, three cases of thyroid gland solitary fibrous tumor were analyzed in conjunction with 35 cases compiled from the English literature. Thyroid gland solitary fibrous tumors showed an equal sex distribution with a mean age at presentation of 54.4 years (range, 28-88 years). The patients typically presented with an asymptomatic, slow growing neck mass. Microscopically, the tumors were characterized by cytologically bland spindle cells with patternless growth, hypocellular and hypercellular areas, variable amounts of collagen, and ectatic, branching blood vessels. Two previous reported tumors were considered to be histologically malignant on the basis of increased mitotic activity, profound pleomorphism and tumor necrosis. Immunohistochemically, the tumor cells are variably positive with CD34, bcl-2, and CD99. STAT6 immunohistochemistry, performed on the current cases, demonstrated a strong, diffuse nuclear expression in all tumors. Among 26 patients with available follow up data (mean 47.3 months), one developed local recurrence and distant metastasis. Solitary fibrous tumors occurring in the thyroid gland are uncommon, but can be reliably diagnosed based on the presence of characteristic morphologic features as well as immunohistochemical expression of STAT6 and CD34. The majority of thyroid gland solitary fibrous tumors have exhibited an indolent clinical course, however experience is limited. The rare potential for aggressive clinical behavior requires clinical surveillance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.