Evidence map›Paper›PMID 30758287›Full record

ArticleeLife2019

Architectural principles for Hfq/Crc-mediated regulation of gene expression.

Xue Yuan Pei, Tom Dendooven, Elisabeth Sonnleitner, Shaoxia Chen, Udo Bläsi, Ben F Luisi

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Article
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  9. Spatial heterogeneity in biofilm metabolism elicited by local control of phenazine methylation.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Potential inhibitory activity of phytoconstituents against black fungus:Computational toxicology (Amsterdam, Netherlands) · 2022
    Article
  17. Article
  18. Article
  19. Rewiring of Gene Expression inFrontiers in microbiology · 2022
    Article
  20. Specific and Global RNA Regulators inInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xue Yuan Pei *Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Tom Dendooven *Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom.
Elisabeth SonnleitnerDepartment of Microbiology, Immunobiology and Genetics, Max F Perutz Laboratories, Center of Molecular Biology, University of Vienna, Vienna Biocenter, Vienna, Austria.
Shaoxia ChenMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Udo BläsiDepartment of Microbiology, Immunobiology and Genetics, Max F Perutz Laboratories, Center of Molecular Biology, University of Vienna, Vienna Biocenter, Vienna, Austria.
Ben F LuisiDepartment of Biochemistry, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0003-1144-9877

Funding

AstraZeneca StudentshipAustrian Science Fund P28711-B22Austrian Science Fund FWF P 28711Medical Research Council MC_U105184326Wellcome Trust 200873/Z/16/Z
6 · The paper itself

Abstract

In diverse bacterial species, the global regulator Hfq contributes to post-transcriptional networks that control expression of numerous genes. Hfq of the opportunistic pathogen

Indexed as

Bacterial ProteinsCatabolite RepressionCryoelectron MicroscopyGene Expression Regulation, BacterialHost Factor 1 ProteinMultiprotein ComplexesPeptide Chain Initiation, TranslationalPromoter Regions, GeneticProtein ConformationPseudomonas aeruginosaRepressor ProteinsRNA, BacterialRNA, MessengerBacterial Proteinscrc protein, PseudomonasHost Factor 1 ProteinMultiprotein ComplexesRepressor ProteinsRNA, BacterialRNA, Messengermetabolic regulationmolecular biophysicsPseudomonas aeruginosariboregulationstructural biology

Identifiers

PMID30758287
PMCPMC6422490

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.