Evidence map›Paper›PMID 30758137›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2019

Unintended consequences of changes to lung allocation policy.

Varun Puri, Ramsey R Hachem, Christian Corbin Frye, Margaret Shea Harrison, Tara R Semenkovich, John P Lynch, Gene Ridolfi, Casey Rowe, Bryan F Meyers, George Alexander Patterson and 8 more

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Activation of donor-derived eosinophils during static storage contributes to primary graft dysfunction after lung transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Development and validation of primary graft dysfunction predictive algorithm for lung transplant candidates.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  9. Article
  10. Same-teams versus different-teams for long distance lung procurement: A cost analysis.The Journal of thoracic and cardiovascular surgery · 2023
    Article
  11. Contemporary trends in PGD incidence, outcomes, and therapies.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2022
    Article
  12. Review
  13. Article
  14. Advanced considerations in organ donors.Journal of thoracic disease · 2021
    Review
  15. Lung transplantation using allografts with more than 8 hours of ischemic time: A single-institution experience.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2021
    Article
  16. Different-team procurements: A potential solution for the unintended consequences of change in lung allocation policy.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

Varun PuriDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Ramsey R HachemDivision of Pulmonary and Critical Care Medicine, Washington University, St. Louis, Missouri.
Christian Corbin FryeDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Margaret Shea HarrisonDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Tara R SemenkovichDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
John P LynchBarnes Jewish Hospital, St. Louis, Missouri.
Gene RidolfiBarnes Jewish Hospital, St. Louis, Missouri.
Casey RoweBarnes Jewish Hospital, St. Louis, Missouri.
Bryan F MeyersDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
George Alexander PattersonDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Benjamin D KozowerDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Michael K PasqueDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Ruben G NavaDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Gary F MarklinMid-America Transplant, St. Louis, Missouri.
Diane BrockmeierMid-America Transplant, St. Louis, Missouri.
Stuart C SweetDivision of Pulmonary and Critical Care Medicine, Washington University, St. Louis, Missouri.ORCID 0000-0002-0638-2586
William C ChapmanDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Daniel KreiselDivision of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.

Funding

The Role of Neutrophils in Regulating Lung Transplant ToleranceP01AI116501 · NIAID · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman · 2015 to 2026
$19.4M
THE ROLE OF ISCHEMIA REPERFUSION INJURY IN LUNG ALLOGRAFT REJECTIONR01HL094601 · NHLBI · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman, Daniel Kreisel · 2009 to 2026
$6.9M
PREDICTIVE MODELING IN LUNG CANCERK07CA178120 · NCI · WASHINGTON UNIVERSITY · PI PURI, VARUN · 2013 to 2017
$789k
Leukocyte trafficking in thoracic graftsI01BX002730 · VA · ST. LOUIS VA MEDICAL CENTER · PI KREISEL, DANIEL · 2016 to 2025
–
BLRD VA I01 BX002730Center for Integrated Healthcare, U.S. Department of Veterans Affairs 1I01BX002730Mid America Transplant Foundation 022017NCI NIH HHS K07 CA178120NHLBI NIH HHS R01 HL094601NIAID NIH HHS P01 AI116501
6 · The paper itself

Abstract

Organ allocation for transplantation aims to balance the principles of justice and medical utility to optimally utilize a scarce resource. To address practical considerations, the United States is divided into 58 donor service areas (DSA), each constituting the first unit of allocation. In November 2017, in response to a lawsuit in New York, an emergency action change to lung allocation policy replaced the DSA level of allocation for donor lungs with a 250 nautical mile circle around the donor hospital. Similar policy changes are being implemented for other organs including heart and liver. Findings from a recent US Department of Health and Human Services report, supplemented with data from our institution, suggest that the emergency policy has not resulted in a change in the type of patients undergoing lung transplantation (LT) or early postoperative outcomes. However, there has been a significant decline in local LT, where donor and recipient are in the same DSA. With procurement teams having to travel greater distances, organ ischemic time has increased and median organ cost has more than doubled. We propose potential solutions for consideration at this critical juncture in the field of transplantation. Policymakers should choose equitable and sustainable access for this lifesaving discipline.

Indexed as

AdultFemaleHumansLung TransplantationMaleMiddle AgedRegional Health PlanningResource AllocationTissue and Organ ProcurementTissue DonorsWaiting Listsclinical research/practicedonors and donationeditorial/personal viewpointlung transplantation/pulmonologyorgan allocationorgan procurement and allocation

Identifiers

PMID30758137
PMCPMC6658330

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.