Evidence map›Paper›PMID 30756484›Full record

ReviewPediatric blood & cancer2019

Understanding, measuring, and addressing the financial impact of cancer on adolescents and young adults.

John M Salsman, Kristin Bingen, Ronald D Barr, David R Freyer

Abstract readReview
In one paragraph

Review in Pediatric blood & cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Mapping and comparing the quality of life outcomes in childhood and adolescent and young adult cancer survivors: an umbrella review and future directions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Effect of group online-based peer support intervention on psychological distress of adolescent and young adult cancer patients: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  6. Trial
  7. Sources of informal financial support among adolescent and young adult cancer survivors: a mixed methods analysis from the HIAYA CHAT study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Trial
  8. Article
  9. Article
  10. The impact of financial toxicity on adolescent/young adult cancer survivors (AYACS): A mixed methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Sociodemographic Factors related to Financial Toxicity among Cancer Patients and Survivors:"The Second Cancer Patient Experience Survey" - A Nationwide Study in Japan.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Arm morbidity and financial difficulty in breast cancer survivors.Journal of cancer survivorship : research and practice · 2026
    Article
  19. Interdependence, marginalisation, and self-acceptance: lived experiences of cancer patients in rural China.International journal of qualitative studies on health and well-being · 2025
    Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

John M SalsmanDepartment of Social Sciences and Health Policy, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Kristin BingenDivision of Hematology/Oncology/Blood and Marrow Transplant, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin.
Ronald D BarrDivision of Hematology/Oncology, Department of Pediatrics, McMaster University, Hamilton, Canada.ORCID 0000-0002-5711-7440
David R FreyerChildren's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Los Angeles, California.ORCID 0000-0001-5280-990X

Funding

COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
ECOG-ACRIN NCORP Research Base - TMISTUG1CA189828 · NCI · ECOG-ACRIN MEDICAL RESEARCH FOUNDATION · PI Peter J ODwyer, MITCHELL D. SCHNALL · 2014 to 2026
$199.7M
Optimizing health related quality of life measurement in adolescent and young adult oncology: A PROMISing solutionR01CA218398 · NCI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SALSMAN, JOHN · 2017 to 2021
$2.6M
NCI NIH HHS R01 CA218398NCI NIH HHS R01 CA218398-01NCI NIH HHS U10 CA098543NCI NIH HHS UG1 CA189828
6 · The paper itself

Abstract

The financial impact of cancer treatment among adolescents and young adults (AYAs, 15-39 years) is deep and long lasting. Compared with other age groups, because of their life stage, AYAs are particularly vulnerable to the adverse economic effects of cancer treatment, also known as financial toxicity. Clinical manifestations of cancer-related financial toxicity include interrupted work and income loss, accumulated debt, treatment nonadherence, avoidance of medical care, and social isolation. Effective clinical interventions should include efforts to increase financial self-efficacy as well as direct support. Measures that are valid, reliable, multidimensional, and age-appropriate are needed to study and address financial toxicity in the AYA population.

Indexed as

IncomeAdolescentAdultCosts and Cost AnalysisFemaleHumansMaleNeoplasmsYoung Adultadolescent and young adult oncologyAYAcancerfinancial impactfinancial toxicityoutcomes researchpsychosocialquality of lifesupportive care

Identifiers

PMID30756484
PMCPMC6777708

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.