Evidence map›Paper›PMID 30756343›Full record

Trial reportJournal of thrombosis and thrombolysis2019

Clinical implications of different risk factor profiles in patients with mesenteric venous thrombosis and systemic venous thromboembolism: a population-based study.

Saman Salim, Moncef Zarrouk, Johan Elf, Anders Gottsäter, Signy Sveinsdottir, Peter Svensson, Stefan Acosta

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Journal of thrombosis and thrombolysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Management of Acute Mesenteric Venous Thrombosis: A Systematic Review of Contemporary Studies.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Primary mesenteric vein thrombosis: a case series.Journal of surgical case reports · 2020
    Article
  9. ABO Blood Groups and Thrombophilia Markers in Patients With Unstimulated Thrombosis in Kurdistan Region of Iraq.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Saman SalimDepartment of Clinical Sciences, Malmö, Lund University, Malmö, Sweden.
Moncef ZarroukDepartment of Clinical Sciences, Malmö, Lund University, Malmö, Sweden.
Johan ElfDepartment of Clinical Sciences, Malmö, Lund University, Malmö, Sweden.
Anders GottsäterDepartment of Clinical Sciences, Malmö, Lund University, Malmö, Sweden.
Signy SveinsdottirDepartment of Translational Medicine, Lund University, Malmö, Sweden.
Peter SvenssonDepartment of Translational Medicine, Lund University, Malmö, Sweden.
Stefan AcostaDepartment of Clinical Sciences, Malmö, Lund University, Malmö, Sweden. Stefan.acosta@med.lu.se.ORCID http://orcid.org/0000-0002-3225-0798
Lund University · SEMalmö University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is unknown whether the risk factor profile for mesenteric venous thrombosis (MVT) is different from systemic venous thromboembolism (VTE). The aim of the present population-based study was to compare acquired and inherited risk factors in MVT versus VTE. Identification of all MVT patients at Skåne University Hospital between 2000 and 2015 was performed in patient records and AuriculA (Swedish anticoagulation registry). VTE patients were retrieved from the Malmö Thrombophilia Study (MATS), including 1465 consecutive unselected VTE patients between 1998 and 2008. Patients with MVT (n = 120) were younger (p < 0.001), had higher glomerular filtration rate (p < 0.001), lower smoking rate (p < 0.001), and had less often undergone recent surgery (p = 0.025). The prevalence of solid cancer (19.2% in MVT versus 12.1% in VTE; p = 0.026) and intra-abdominal cancer (16.7% versus 2.3%; p < 0.001) were higher in MVT. The prevalence of factor V Leiden mutation without presence of cancer was lower in MVT compared to VTE (26.6% versus 38.9%; p = 0.031). Thirty-day mortality was higher in the MVT group (9.2% versus 0.6%; p < 0.001), but did not differ at long-term follow-up according to Kaplan-Meier analysis (p = 0.73). Patients with MVT have a higher prevalence of cancer and lower prevalence of factor V Leiden mutation than those with systemic VTE. Intra-abdominal cancer should be excluded in MVT patients, and the high prevalence of factor V Leiden mutation in patients without cancer in both groups suggests that screening for thrombophilia in patients without cancer should be considered in this population for both groups.

Indexed as

Mesenteric VeinsMutation, MissenseNeoplasmsThrombophiliaThrombosisAdultAgedFactor VFemaleFollow-Up StudiesHumansMaleMiddle AgedPrevalenceRisk FactorsVenous ThromboembolismFactor Vfactor V LeidenFactor V Leiden mutationMesenteric venous thrombosisProthrombin mutationThrombophilia testingVenous thromboembolism

Identifiers

PMID30756343
PMCPMC6476820
OpenAlexW2913432681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.