Evidence map›Paper›PMID 30756263›Full record

ArticleAnnals of biomedical engineering2019

Pulse Arrival Time and Pulse Interval as Accurate Markers to Detect Mechanical Alternans.

Stefan van Duijvenboden, Ben Hanson, Nick Child, Pier D Lambiase, Christopher A Rinaldi, Gill Jaswinder, Peter Taggart, Michele Orini

Open access · hybridAbstract read
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In one paragraph

Article in Annals of biomedical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Stefan van DuijvenbodenInstitute of Cardiovascular Science, University College London, London, UK. ucemvan@ucl.ac.uk.ORCID http://orcid.org/0000-0001-8897-558X
Ben HansonDepartment of Mechanical Engineering, University College London, London, UK.
Nick ChildDepartment of Cardiology, Guy's and St. Thomas's Hospital, London, UK.
Pier D LambiaseInstitute of Cardiovascular Science, University College London, London, UK.
Christopher A RinaldiDepartment of Cardiology, Guy's and St. Thomas's Hospital, London, UK.
Gill JaswinderDepartment of Cardiology, Guy's and St. Thomas's Hospital, London, UK.
Peter TaggartInstitute of Cardiovascular Science, University College London, London, UK.
Michele OriniDepartment of Mechanical Engineering, University College London, London, UK.
St Thomas' Hospital · GBSt Bartholomew's Hospital · GBUniversity College London · GBQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mechanical alternans (MA) is a powerful predictor of adverse prognosis in patients with heart failure and cardiomyopathy, but its use remains limited due to the need of invasive continuous arterial pressure recordings. This study aims to assess novel cardiovascular correlates of MA in the intact human heart to facilitate affordable and non-invasive detection of MA and advance our understanding of the underlying pathophysiology. Arterial pressure, respiration, and ECG were recorded in 12 subjects with healthy ventricles during voluntarily controlled breathing at different respiratory rate, before and after administration of beta-blockers. MA was induced by ventricular pacing. A total of 67 recordings lasting approximately 90 s each were analyzed. Mechanical alternans (MA) was measured in the systolic blood pressure. We studied cardiovascular correlates of MA, including maximum pressure rise during systole (dPdt

Indexed as

Blood PressureHeart RateMyocardial ContractionRespiratory MechanicsAdultFemaleHeart FailureHumansMaleMiddle AgedPulseElectrical alternansMechancial alternansPulse arrival timePulse transit time

Identifiers

PMID30756263
PMCPMC6453876
OpenAlexW2914608960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.