Evidence map›Paper›PMID 30756170›Full record

SynthesisJournal of neurology2019

Anger, hostility and risk of stroke: a meta-analysis of cohort studies.

Hanze Chen, Beidi Zhang, Weishuang Xue, Jinwei Li, Yuru Li, Kailei Fu, Xinxin Chen, Miao Sun, Han Shi, Li Tian and 1 more

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hanze ChenDepartment of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, China.
Beidi ZhangDepartment of Endodontics, School of Stomatology, China Medical University, Shenyang, China.
Weishuang XueDepartment of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, China.
Jinwei LiDepartment of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, China.
Yuru LiDepartment of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, China.
Kailei FuDepartment of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, China.
Xinxin ChenDepartment of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, China.
Miao SunDepartment of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, China.
Han ShiClinical Department One, China Medical University, Shenyang, China.
Li TianDepartment of Geriatrics, Shengjing Hospital, China Medical University, Shenyang, China. tianlicmu2@126.com.
Weiyu TengDepartment of Neurology, The First Affiliated Hospital, China Medical University, Shenyang, China. tengweiyucmu@sina.com.

Funding

China Medical University Major Clinical Medicine Construction Project in 2018 111-3110118036National science and Technology Major Project 2017ZX10201101
6 · The paper itself

Abstract

objectiveA growing number of studies have been conducted on the relationship between anger and hostility and the risk of stroke, and their conclusions are not consistent. Accordingly, we performed a meta-analysis to evaluate the relationship between anger and hostility and the risk of stroke.

methodsWe searched the PubMed and Embase databases for cohort studies, focusing on the relationship between anger and hostility and risk of stroke. Then studies were selected according to the inclusion and exclusion criteria. Study results were pooled using a random effects model.

resultsTen studies from seven articles involving 52,277 participants were included in this meta-analysis. No significant association was found between anger and hostility level and risk of stroke (hazard ratio 1.08; 95% confidence interval 0.79-1.47). However, a positive association was seen when people with high socioeconomic status were excluded (hazard ratio 1.30; 95% confidence interval 1.06-1.59).

conclusionA higher level of anger and hostility is not associated with elevated risk of stroke. However, the association is positive among people with lower socioeconomic status.

Indexed as

AngerHostilityHumansStrokeAngerCohort studiesHostilityMeta-analysisStroke

Identifiers

PMID30756170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.