Evidence map›Paper›PMID 30756148›Full record

ArticleSocial psychiatry and psychiatric epidemiology2019

Psychiatric comorbidity as a risk factor for the mortality of people with bulimia nervosa.

Hubertus Himmerich, Matthew Hotopf, Hitesh Shetty, Ulrike Schmidt, Janet Treasure, Richard D Hayes, Robert Stewart, Chin-Kuo Chang

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. rTMS Therapy for Eating Disorders: Scoping Review on Efficacy, Safety, Stimulation Parameters and Study Subjects.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Bulimia Nervosa and Binge-Eating Disorder Across the Lifespan.Focus (American Psychiatric Publishing) · 2024
    Review
  10. Article
  11. Review
  12. Mortality and care of eating disorders.Acta psychiatrica Scandinavica · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hubertus HimmerichDepartment of Psychological Medicine, King's College London, London, UK.
Matthew HotopfDepartment of Psychological Medicine, King's College London, London, UK.
Hitesh ShettySouth London and Maudsley NHS Foundation Trust, London, UK.
Ulrike SchmidtDepartment of Psychological Medicine, King's College London, London, UK.
Janet TreasureDepartment of Psychological Medicine, King's College London, London, UK.
Richard D HayesDepartment of Psychological Medicine, King's College London, London, UK.
Robert StewartDepartment of Psychological Medicine, King's College London, London, UK.
Chin-Kuo ChangDepartment of Psychological Medicine, King's College London, London, UK. ckchang@utaipei.edu.tw.
King's College London · GBSouth London and Maudsley NHS Foundation Trust · GB

Funding

Medical Research Council MC_PC_17214National Institute for Health Research BRC-2011-10035
6 · The paper itself

Abstract

backgroundBulimia nervosa (BN) is associated with increased mortality. Frequent comorbidities of BN include substance use disorders, affective disorders and personality disorders (PD). These comorbidities may add an additional risk for mortality.

methodsWe investigated the influence of these psychiatric comorbidities on all-cause mortality with demographic and socioeconomic factors considered as confounders over an observation period from January 2007 to March 2016 for 1501 people with BN using anonymised health records data from the South London and Maudsley NHS Foundation Trust (SLaM), retrieved through its Clinical Records Interactive Search (CRIS) data resource. Mortality was ascertained through monthly linkages to the nationwide tracing system administered by the Office for National Statistics (ONS). We used Cox proportional hazards regression to calculate hazard ratios (HRs) with 95% confidence intervals (CIs). Multivariable analyses were also performed to estimate effects when controlling for confounding of age, sex, ethnicity, borough, marital status and deprivation score.

resultsA total of 18 patients with BN died during the observation period. The standardised mortality ratio (SMR) for our study cohort (against the population of England and Wales in 2012 as a standard) was 2.52 (95% CI 1.49-3.97). Cox regressions revealed significant associations of mortality with older age and male gender. Comorbid PD (HR: 3.36; 95% CI 1.05-10.73) was significantly associated with all-cause mortality, even after controlling for demographic and socioeconomic covariates.

conclusionsThese results highlight increased mortality in patients with BN and the importance of recognising and treating PDs in patients with BN.

Indexed as

AdultAgedBulimia NervosaCause of DeathCohort StudiesComorbidityEnglandFemaleHumansMaleMiddle AgedMood DisordersPersonality DisordersProportional Hazards ModelsRisk FactorsSocioeconomic FactorsAffective disordersBulimia nervosaEating disorderPersonality disorderPsychiatric comorbiditiesSubstance use disorders

Identifiers

PMID30756148
OpenAlexW2912679480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.