Evidence map›Paper›PMID 30755925›Full record

ArticleEuropean journal of case reports in internal medicine2017

TSH-Suppressive Therapy: A Thorny Issue.

Itala Marina Baldini, Cristina Cocino, Sonia Seghezzi, Maria Domenica Cappellini

Abstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Itala Marina BaldiniUOC Medicina Interna, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
Cristina CocinoUOC Medicina Interna, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.
Sonia SeghezziICH Humanitas, EAS Pronto Soccorso, Rozzano (MI), Italy.
Maria Domenica CappelliniUOC Medicina Interna, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid stimulating hormone (TSH)-suppressive therapy with levothyroxine is a cornerstone of thyroid carcinoma follow-up therapy, but the achievement of therapeutic goals must be balanced against L-T4 side effects. We describe the case of a 64-year-old cardiopathic patient with papillary thyroid carcinoma and autoimmune thyroiditis, whose cardiac condition worsened during TSH-suppressive therapy. TSH concentrations also fluctuated widely because of changing intestinal absorption due to coeliac disease. LEARNING POINTS: TSH-suppressive therapy with levothyroxine (L-T4) to prevent thyroid carcinoma relapse can be a tricky problem in the presence of comorbidities.The recent American Thyroid Association guidelines are a useful reference for complex cases of thyroid carcinoma.When strict TSH control is crucial, the L-T4 liquid solution may be a valuable tool.

Indexed as

intestinal malabsorptionThyroid carcinomaTSH-suppressive therapy

Identifiers

PMID30755925
PMCPMC6346897

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.