ArticleAmerican journal of cancer research2019
Neural correlates of chemotherapy-induced emotion regulation impairment in breast cancer patients.
Article in American journal of cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 3 citations in OpenAlex.
- Artificial intelligence-driven pharmacovigilance analysis of polypharmacy and adverse events in breast cancer survivors treated with antidepressants.International journal of surgery (London, England) · 2026Article
- The alterations in event-related potential responses to pain empathy in breast cancer survivors treated with chemotherapy.Frontiers in psychology · 2022Article
- Changes in plasma IL-1β, TNF-α and IL-4 levels are involved in chemotherapy-related cognitive impairment in early-stage breast cancer patients.American journal of translational research · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
To investigate the chemotherapy-induced emotion regulation impairment and its neural correlates in breast cancer (BC) patients by event-related potentials (ERP), seventeen BC patients were investigated on emotion regulation paradigms while undergoing the recording of an event-related potential (ERP) both before and after chemotherapy. The performance of behavioral and ERP was compared for the data collected before and after chemotherapy (BCB and BCA, respectively). The correlation of the difference between the peak and the latency of each component before and after chemotherapy were compared with the difference in behavior (RT and AR). BC patients showed a lower accuracy rate in both explicit and implicit emotion identification in BCA compared to that in BCB. Further, both the N1 and P2 components were significantly delayed. The peak values of the N1 and P2 in BCA were significantly higher than those in BCB, whereas the peak value of the N2 in BCA was significantly lower than that in BCB. There was a positive correlation between the difference in latency at the CZ (r=0.88), F3 (r=0.97) and FZ (r=0.85) points in the N1 component and the RT. The difference in latency at the FCZ point in the N2 (r=0.88) component is positively correlated with the AR. The difference in peak value at the CPZ (r=0.89) point in the N1 component is positively correlated with the RT. Both the implicit and explicit emotional processing was compromised in BC patients following chemotherapy. These emotional processing deficits may be related to the changes of the N1, N2 and P2 of the ERP.
Indexed as
Identifiers
30755820PMC6356929W2989030916What OpenQuestion holds
Registered trials
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