Evidence map›Paper›PMID 30755706›Full record

ArticleLeukemia2019

GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations.

Paolo Sportoletti, Letizia Celani, Emanuela Varasano, Roberta Rossi, Daniele Sorcini, Chiara Rompietti, Francesca Strozzini, Beatrice Del Papa, Valerio Guarente, Giulio Spinozzi and 6 more

Open access · hybridAbstract readLetter
In one paragraph

Article in Leukemia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Hematopoietic Stem Cells and the Immune System in Development and Aging.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Article
  8. IntegratedCells · 2021
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Paolo SportolettiCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy. paolo.sportoletti@unipg.it.ORCID http://orcid.org/0000-0002-5630-9862
Letizia CelaniCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Emanuela VarasanoCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Roberta RossiCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Daniele SorciniCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Chiara RompiettiCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Francesca StrozziniCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Beatrice Del PapaCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Valerio GuarenteCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Giulio SpinozziCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Debora CecchiniCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Oxana BereshchenkoSection of Pharmacology, Toxicology and Chemotherapy, University of Perugia, Perugia, 06132, Italy.
Torsten HaferlachMLL Munich Leukemia Laboratory, Munich, 81377, Germany.
Maria Paola MartelliCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Franca FalzettiCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy.
Brunangelo FaliniCentro di Ricerca Emato-Oncologica (CREO), University of Perugia, Perugia, 06132, Italy. brunangelo.falini@unipg.it.
University of Perugia · ITMunich Leukemia Laboratory (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Epigenesis, GeneticMutationAnimalsBiomarkers, TumorFemalefms-Like Tyrosine Kinase 3GATA1 Transcription FactorGene Expression Regulation, NeoplasticHumansLeukemia, Myeloid, AcuteMiceMice, KnockoutNuclear ProteinsNucleophosminPrognosisTandem Repeat SequencesBiomarkers, TumorFLT3 protein, humanFlt3 protein, mousefms-Like Tyrosine Kinase 3GATA1 protein, humanGata1 protein, mouseGATA1 Transcription FactorNPM1 protein, humanNpm1 protein, mouseNuclear ProteinsNucleophosmin

Identifiers

PMID30755706
PMCPMC6756200
OpenAlexW2911664912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.