Evidence map›Paper›PMID 30755647›Full record

ArticleScientific reports2019

Multilayer fabrication of unobtrusive poly(dimethylsiloxane) nanobrush for tunable cell adhesion.

Soo Sang Chae, Joo Hyun Jung, Won Jin Choi, Joung Kyu Park, Hong Koo Baik, Jongjin Jung, Hyuk Wan Ko

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Silicone Oil-Grafted Low-Hysteresis Water-Repellent Surfaces.ACS applied materials & interfaces · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Soo Sang ChaeDepartment of Materials Science and Engineering, Yonsei University, Seoul, 03722, Korea.
Joo Hyun JungDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Korea.
Won Jin ChoiAdvanced Materials Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, 34114, Korea.
Joung Kyu ParkAdvanced Materials Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, 34114, Korea.
Hong Koo BaikDepartment of Materials Science and Engineering, Yonsei University, Seoul, 03722, Korea. thinfilm@yonsei.ac.kr.
Jongjin JungDepartment of Chemistry, Hannam University, Daejeon, 34054, Korea. jongjin9@hnu.kr.
Hyuk Wan KoDepartment of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Korea. kohw@yonsei.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise modulation of polymer brush in its thickness and grafting density can cause unexpected cell behaviors and regulated bioactivities. Herein, a nanoscale poly(dimethylsiloxane) (PDMS) brush was employed to use as a controllable material for cell adhesion. Facile fabrication of ultrathin monolayer PDMS nanobrush on an underlying substrate facilitated regaining cell adhesion through long-range cell attractive forces such as the van der Waals forces. We showed that cell adhesion is diminished by increasing the number of nanobrush layers, causing a gradual decrease of the effectiveness of the long-range force. The result demonstrates that ultrathin PDMS nanobrush can either promote or inhibit cell adhesion, which is required for various biomedical fields such as tissue-engineering, anti-fouling coating, and implantable biomaterials and sensors.

Indexed as

AnimalsBiocompatible MaterialsBiosensing TechniquesCell AdhesionCell Culture TechniquesCell Line, TumorDimethylpolysiloxanesHeLa CellsHumansHydrophobic and Hydrophilic InteractionsMaterials TestingMiceMicroscopy, ConfocalMicroscopy, FluorescenceNanostructuresNIH 3T3 CellsbaysilonBiocompatible MaterialsDimethylpolysiloxanesOxygenPolymers

Identifiers

PMID30755647
PMCPMC6372672

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.