ArticleProceedings of the National Academy of Sciences of the United States of America2019
Stage-dependent cardiac regeneration in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 59 citations in OpenAlex.
- Organ-Specific Shifts in Aerobic and Anaerobic Metabolism Throughout Metamorphosis Into Adulthood in a Fully Aquatic Amphibian.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Article
- Knockout of thyroid hormone receptor alpha a (thraa) enhances cardiac regeneration in zebrafish through metabolic and hypoxic regulation.Cell communication and signaling : CCS · 2025Article
- Neuronal activation in the axolotl brain promotes tail regeneration.NPJ Regenerative medicine · 2025Article
- Thyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration.BMC genomics · 2024Article
- Animal models to study cardiac regeneration.Nature reviews. Cardiology · 2024Review
- Inter-organ communication during tissue regeneration.Development (Cambridge, England) · 2023Review
- Thyroid hormone as a temporal switch in mouse development.European thyroid journal · 2023Review
- Thyroid hormone receptor knockout prevents the loss of Xenopus tail regeneration capacity at metamorphic climax.Cell & bioscience · 2023Article
- Ageing across the great divide: tissue transformation, organismal growth and temperature shape telomere dynamics through the metamorphic transition.Proceedings. Biological sciences · 2023Article
- Essential and subtype-dependent function of thyroid hormone receptors during Xenopus metamorphosis.Vitamins and hormones · 2023Review
- Steroid-receptor coactivator complexes in thyroid hormone-regulation of Xenopus metamorphosis.Vitamins and hormones · 2023Article
- Upregulation of proto-oncogene ski by thyroid hormone in the intestine and tail during Xenopus metamorphosis.General and comparative endocrinology · 2022Article
- Cell landscape of larval and adult Xenopus laevis at single-cell resolution.Nature communications · 2022Article
- Enhancer selection dictates gene expression responses in remote organs during tissue regeneration.Nature cell biology · 2022Article
- Ecdysone exerts biphasic control of regenerative signaling, coordinating the completion of regeneration with developmental progression.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Why Has the Ability to Regenerate Following CNS Injury Been Repeatedly Lost Over the Course of Evolution?Frontiers in neuroscience · 2022Article
- Innate Mechanisms of Heart Regeneration.Cold Spring Harbor perspectives in biology · 2021Review
- Endocrine Influence on Cardiac Metabolism in Development and Regeneration.Endocrinology · 2021Review
- Biodiversity-based development and evolution: the emerging research systems in model and non-model organisms.Science China. Life sciences · 2021Review
- Fosl1 is vital to heart regeneration upon apex resection in adult Xenopus tropicalis.NPJ Regenerative medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite therapeutic advances, heart failure is the major cause of morbidity and mortality worldwide, but why cardiac regenerative capacity is lost in adult humans remains an enigma. Cardiac regenerative capacity widely varies across vertebrates. Zebrafish and newt hearts regenerate throughout life. In mice, this ability is lost in the first postnatal week, a period physiologically similar to thyroid hormone (TH)-regulated metamorphosis in anuran amphibians. We thus assessed heart regeneration in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.