ArticleProceedings of the National Academy of Sciences of the United States of America2019
PILS6 is a temperature-sensitive regulator of nuclear auxin input and organ growth in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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Who cites it
61 citing papers in PubMed.
- Metabolism meets transport: a new perspective on auxin homeostasis at subcellular level.Planta · 2026Review
- Shaping Plant Adaptation in a Warmer World: Developmental Plasticity Under Moderately Elevated Temperatures.Plants (Basel, Switzerland) · 2026Review
- Genome-Wide Identification of the PIN-LIKES (Current issues in molecular biology · 2026Article
- Comparative transcriptome analysis provides insights into the dwarfing mechanism of pear trees.BMC genomic data · 2026Article
- Heat acclimation induces AcLBD1 activated AcHSFA2s mutual amplification cascade for rapid recovery of root vitality and leaf photosynthesis in kiwifruit.Frontiers in plant science · 2026Article
- A novel role of BPCs in the control of medial domain differentiation during gynoecium development in Arabidopsis thaliana.Plant molecular biology · 2025Article
- Hormonal regulation of root growth under moderately elevated temperatures.Annals of botany · 2025Review
- A localized disruption in auxin status leading to root system defects under elevated temperature environments.Plant cell reports · 2025Article
- Integrated transcriptome-metabolome analysis reveals oleanolic acid as a central regulator of heat stress adaptation in Rhododendron moulmainense.BMC plant biology · 2025Article
- ERAD machinery controls the conditional turnover of PIN-LIKES in plants.Science advances · 2025Article
- Comparative Transcriptome Analysis ofInternational journal of molecular sciences · 2025Article
- RETINOBLASTOMA-RELATED Has Both Canonical and Noncanonical Regulatory Functions During Thermo-Morphogenic Responses in Arabidopsis Seedlings.Plant, cell & environment · 2025Article
- How Do Arabidopsis Seedlings Sense and React to Increasing Ambient Temperatures?Plants (Basel, Switzerland) · 2025Article
- Distinct gene reprogramming in rosetted and symptomless shoots from the same mature rose plants infected with rose rosette virus.Frontiers in plant science · 2025Article
- Heat stress suppresses DNA replication and mitosis in barley root apical meristems.Frontiers in plant science · 2025Article
- Nutrient levels control root growth responses to high ambient temperature in plants.Nature communications · 2024Article
- ZmPILS6 is an auxin efflux carrier required for maize root morphogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Plants and global warming: challenges and strategies for a warming world.Plant cell reports · 2024Review
- Article
- Root Hair Imaging Using Confocal Microscopy.Methods in molecular biology (Clifton, N.J.) · 2024Article
1 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors.
Funding
Abstract
Temperature modulates growth and development throughout the entire lifecycle of a plant. High temperature (HT) triggers the auxin biosynthesis-dependent growth in aerial tissues. On the other hand, the contribution of auxin to HT-induced root growth is currently under debate. Here we show that the putative intracellular auxin carrier PIN-LIKES 6 (PILS6) is a negative regulator of organ growth and that its abundance is highly sensitive to HT. PILS6 localizes to the endoplasmic reticulum and limits the nuclear availability of auxin, consequently reducing the auxin signaling output. HT represses the PILS6 protein abundance, which impacts on PILS6-dependent auxin signaling in roots and root expansion. Accordingly, we hypothesize that PILS6 is part of an alternative mechanism linking HT to auxin responses in roots.
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