Evidence map›Paper›PMID 30755524›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Cold sensing by Na

A P Luiz, D I MacDonald, S Santana-Varela, Q Millet, S Sikandar, J N Wood, E C Emery

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. GCN2 regulates paclitaxel-induced neuropathic pain.British journal of pharmacology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Ion channels of cold transduction and transmission.The Journal of general physiology · 2024
    Review
  11. Article
  12. Article
  13. Thermosensation and TRP Channels.Advances in experimental medicine and biology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

A P LuizMolecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom.
D I MacDonaldMolecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom.
S Santana-VarelaMolecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom.
Q MilletMolecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom.
S SikandarMolecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom.
J N WoodMolecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom J.Wood@ucl.ac.uk e.emery@ucl.ac.uk.ORCID 0000-0002-9166-8158
E C EmeryMolecular Nociception Group, Wolfson Institute for Biomedical Research, University College London, London WC1E 6BT, United Kingdom J.Wood@ucl.ac.uk e.emery@ucl.ac.uk.ORCID 0000-0001-9723-8661
University College London · GB

Funding

Versus Arthritis 21734Wellcome Trust 200183/Z/15/ZWellcome Trust WT101054/Z/13/ZWellcome Trust WT200183/Z/15/Z
6 · The paper itself

Abstract

The ability to detect environmental cold serves as an important survival tool. The sodium channels Na

Indexed as

AnimalsCold TemperatureGanglia, SpinalMiceNAV1.8 Voltage-Gated Sodium ChannelNociceptorsPotassium ChannelsSensory Receptor CellsThermosensingTRPM Cation ChannelsNAV1.8 Voltage-Gated Sodium ChannelPotassium ChannelsScn10a protein, mouseTASK3 protein, mouseTRPM8 protein, mouseTRPM Cation ChannelscoldGCaMPNaV1.8nociceptionTrpm8

Identifiers

PMID30755524
PMCPMC6397562
OpenAlexW2914287773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.