Evidence map›Paper›PMID 30755168›Full record

ArticleBMC neurology2019

Stroke prevention in patients with acute ischemic stroke and atrial fibrillation in Germany - a cross sectional survey.

Alexander Wutzler, Christos Krogias, Anna Grau, Roland Veltkamp, Peter U Heuschmann, Karl Georg Haeusler

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Etiology of recurrent large vessel occlusions treated with repeated thrombectomy.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Alexander WutzlerCardiovascular Center, St. Josef Hospital, University Hospital of the Ruhr-University Bochum, Bochum, Germany.
Christos KrogiasDepartment of Neurology, St. Josef Hospital, University Hospital of the Ruhr-University Bochum, Bochum, Germany.
Anna GrauInstitute of Clinical Epidemiology and Biometry, University Würzburg, Würzburg, Germany.
Roland VeltkampDepartment of Stroke Medicine, Department of Neurology, Alfried Krupp Krankenhaus, Essen, Germany & Department of Neurology, Imperial College London UK, University Hospital Heidelberg, Heidelberg, Germany.
Peter U HeuschmannInstitute of Clinical Epidemiology and Biometry, University Würzburg, Würzburg, Germany.
Karl Georg HaeuslerDepartment of Neurology, University Hospital Würzburg, Josef-Schneider-Str. 11, 97080, Würzburg, Germany. Haeusler_K@ukw.de.
Zimmer Biomet (Germany) · DEHeidelberg University · DERuhr University Bochum · DESt. Josef-Hospital · DEUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is present in 15-20% of patients with acute ischemic stroke. Oral anticoagulation reduces the risk of AF-related recurrent stroke but clinical guideline recommendations are rather vague regarding its use in the acute phase of stroke. We aimed to assess the current clinical practice of medical stroke prevention in AF patients during the acute phase of ischemic stroke.

methodsIn April 2017, a standardized anonymous questionnaire was sent to clinical leads of all 298 certified stroke units in Germany.

resultsOverall, 154 stroke unit leads participated (response rate 52%). Anticoagulation in the acute phase of stroke is considered feasible in more than 90% of AF patients with ischemic stroke. Clinicians assume that about two thirds of all AF patients (range 20-100%) are discharged on oral anticoagulation. According to local preferences, acetylsalicylic acid is given orally in the majority of patients with delayed initiation of oral anticoagulation. A non-vitamin K-dependent oral anticoagulant (NOAC) is more often prescribed than a vitamin K-dependent oral anticoagulant (VKA). VKA is more often chosen in patients with previous VKA intake than in VKA naive patients. In the minority of patients, stroke unit leads discuss the prescription of a specific oral anticoagulant with the treating general practitioner. Adherence to medical stroke prevention after hospital discharge is not assessed on a regular basis in any patient by the majority of participating stroke centers.

conclusionsEarly secondary stroke prevention in AF patients in German stroke units is based on OAC use but prescription modalities vary in clinical practice.

Indexed as

AgedAnticoagulantsAspirinAtrial FibrillationCross-Sectional StudiesFemaleGermanyHumansMaleMiddle AgedRecurrenceRisk FactorsSecondary PreventionStrokeVitamin KAnticoagulantsAspirinVitamin KAtrial fibrillationIschemic strokeOral anticoagulationSecondary stroke preventionStroke unitSurvey

Identifiers

PMID30755168
PMCPMC6371606
OpenAlexW2927063642

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.