Evidence map›Paper›PMID 30755154›Full record

Trial reportBMC gastroenterology2019

Moderate-intensity aerobic and resistance exercise is safe and favorably influences body composition in patients with quiescent Inflammatory Bowel Disease: a randomized controlled cross-over trial.

Owen Cronin, Wiley Barton, Carthage Moran, Donal Sheehan, Ronan Whiston, Helena Nugent, Yvonne McCarthy, Catherine B Molloy, Orla O'Sullivan, Paul D Cotter and 2 more

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 47 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02463916 phase2unknown statusnot on this map

The ExMET-IBD Study: A Randomized Control Trial to Determine the Effects of Exercise on Intestinal Microbiota and Immunological Markers in Patients With Inflammatory Bowel Disease and Rheumatoid Arthritis

TypeinterventionalSponsorUniversity College CorkRan2015 to 2016Enrolled60ConditionsInflammatory Bowel Disease, Rheumatoid ArthritisArmsExercise
NCT05174754 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Impact Of A Physician-led Exercise Programme On Quality Of Life, Muscle Mass And Clinical Response In Inflammatory Bowel Disease Patients During Induction With Medical Therapy

TypeinterventionalSponsorRoyal College of Surgeons, IrelandRan2022 to 2023Enrolled70ConditionsInflammatory Bowel DiseasesArmsPhysician-prescribed Exercise Programme, Best Medical Therapy
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Owen CroninDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland. owen.cronin@hotmail.com.ORCID http://orcid.org/0000-0002-1365-9942
Wiley BartonDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland.
Carthage MoranDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland.
Donal SheehanDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland.
Ronan WhistonTeagasc Food Research Centre, Moorepark, Fermoy, P61 C996, Cork, Ireland.
Helena NugentDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland.
Yvonne McCarthyDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland.
Catherine B MolloyDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland.
Orla O'SullivanAPC Microbiome Ireland, National University of Ireland, Cork, T12 YT20, Ireland.
Paul D CotterAPC Microbiome Ireland, National University of Ireland, Cork, T12 YT20, Ireland.
Michael G MolloyDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland.
Fergus ShanahanDepartment of Medicine, National University of Ireland, University College Cork, Cork University Hospital, Wilton, T12 DC4A, Cork, Ireland.

Funding

Irish Centre for Arthritis Research and Education N/aScience Foundation Ireland 11/PI/1137Science Foundation Ireland 13/SIRG/2160Science Foundation Ireland SFI/12/RC/2273
6 · The paper itself

Abstract

backgroundOverweight and metabolic problems now add to the burden of illness in patients with Inflammatory Bowel Disease. We aimed to determine if a program of aerobic and resistance exercise could safely achieve body composition changes in patients with Inflammatory Bowel Disease.

methodsA randomized, cross-over trial of eight weeks combined aerobic and resistance training on body composition assessed by Dual Energy X-ray Absorptiometry was performed. Patients in clinical remission and physically inactive with a mean age of 25 ± 6.5 years and Body Mass Index of 28.9 ± 3.8 were recruited from a dedicated Inflammatory Bowel Disease clinic. Serum cytokines were quantified, and microbiota assessed using metagenomic sequencing.

resultsImproved physical fitness was demonstrated in the exercise group by increases in median estimated VO

conclusionsModerate-intensity combined aerobic and resistance training is safe in physically unfit patients with quiescent Inflammatory Bowel Disease and can quickly achieve favourable body compositional changes without adverse effects.

trial registrationThe study was registered at ClinicalTrials.gov; Trial number: NCT02463916 .

Indexed as

Body CompositionExerciseResistance TrainingAdultAffectBody Mass IndexCross-Over StudiesCytokinesFemaleGastrointestinal MicrobiomeHumansInflammatory Bowel DiseasesMaleOverweightProspective StudiesQuality of LifeCytokinesBody compositionClinical trialsExerciseMicrobiome

Identifiers

PMID30755154
PMCPMC6373036

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.