Evidence map›Paper›PMID 30754716›Full record

ArticleBiomolecules2019

Triterpene Derivatives as Relevant Scaffold for New Antibiofilm Drugs.

Gloria Narjara Santos da Silva, Muriel Primon-Barros, Alexandre José Macedo, Simone Cristina Baggio Gnoatto

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Exploring Plant-Based Compounds as Alternatives for TargetingInternational journal of molecular sciences · 2024
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  8. Delving into the Mechanisms of Sponge-AssociatedMolecules (Basel, Switzerland) · 2023
    Article
  9. Resistance profile and biofilm production of Enterococcus spp., Staphylococcus sp., and Streptococcus spp. from dairy farms in southern Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  10. Bacterial Foodborne Illness in Malaysia:The Malaysian journal of medical sciences : MJMS · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Gloria Narjara Santos da SilvaLaboratório de Fitoquímica e Síntese Orgânica, Faculdade de Farmácia, Universidade Federaldo Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, 90610-000, Brasil. narjarags@gmail.com.
Muriel Primon-BarrosLaboratório de Biofilmes e Diversidade, Faculdade de Farmácia and Centro de Biotecnologia, UniversidadeFederal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, 91501-970, Brasil. murielprimon@gmail.com.
Alexandre José MacedoLaboratório de Biofilmes e Diversidade, Faculdade de Farmácia and Centro de Biotecnologia, UniversidadeFederal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, 91501-970, Brasil. alexandre.macedo@ufrgs.br.
Simone Cristina Baggio GnoattoLaboratório de Fitoquímica e Síntese Orgânica, Faculdade de Farmácia, Universidade Federaldo Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, 90610-000, Brasil. simone.gnoatto@ufrgs.br.
Universidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New medicines for the treatment of bacterial biofilm formation are required. For thisreason, this study shows the in vitro activity of betulinic acid (BA), ursolic acid (UA) and their twentyderivatives against planktonic and biofilm cells (gram-positive bacterial pathogens: Enterococcusfaecalis,

Indexed as

AnimalsAnti-Bacterial AgentsBetulinic AcidBiofilmsChlorocebus aethiopsDose-Response Relationship, DrugEnterococcus faecalisMicrobial Sensitivity TestsMolecular ConformationPentacyclic TriterpenesStaphylococcus aureusStaphylococcus epidermidisStructure-Activity RelationshipTriterpenesUrsolic AcidVero CellsAnti-Bacterial AgentsBetulinic AcidPentacyclic TriterpenesTriterpenesUrsolic Acidbacterial pathogensbetulinic acidcytotoxicitypathogenic biofilmsUrsolic acid

Identifiers

PMID30754716
PMCPMC6406419
OpenAlexW2913193040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.