ArticleMicromachines2019
Microfluidic High-Migratory Cell Collector Suppressing Artifacts Caused by Microstructures.
Article in Micromachines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Microvalve with Trapezoid-Shaped Cross-Section for Deep Microchannels.Micromachines · 2021Article
- Cell Culture on Low-Fluorescence and High-Resolution Photoresist.Micromachines · 2020Article
- Portable Rice Disease Spores Capture and Detection Method Using Diffraction Fingerprints on Microfluidic Chip.Micromachines · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
The small number of high-migratory cancer cells in a cell population make studies on high-migratory cancer cells difficult. For the development of migration assays for such cancer cells, several microfluidic devices have been developed. However, they measure migration that is influenced by microstructures and they collect not only high-migratory cells, but also surrounding cells. In order to find high-migratory cells in cell populations while suppressing artifacts and to collect these cells while minimizing damages, we developed a microfluidic high-migratory cell collector with the ability to sort cancer cells according to cellular migration and mechanical detachment. High-migratory cancer cells travel further from the starting line when all of the cells are seeded on the same starting line. The high-migratory cells are detached using a stretch of cell adhesive surface using a water-driven balloon actuator. Using this cell collector, we selected high-migratory HeLa cells that migrated about 100m in 12 h and collected the cells.
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Registered trials
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