Evidence map›Paper›PMID 30754677›Full record

ReviewBioengineering (Basel, Switzerland)2019

Application of Metal Nanoparticle⁻Hydrogel Composites in Tissue Regeneration.

Hui-Li Tan, Sin-Yeang Teow, Janarthanan Pushpamalar

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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  4. Advances in hydrogel research: a 25-year bibliometric overview.Journal of materials science. Materials in medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hui-Li TanSchool of Science, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, 47500 Selangor Darul Ehsan, Malaysia. hui.tan@monash.edu.
Sin-Yeang TeowDepartment of Medical Sciences, School of Healthcare and Medical Sciences, Sunway University, Jalan Universiti, Bandar Sunway, 47500 Selangor Darul Ehsan, Malaysia. ronaldt@sunway.edu.my.
Janarthanan PushpamalarSchool of Science, Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, Subang Jaya, 47500 Selangor Darul Ehsan, Malaysia. pushpa.janarthanan@monash.edu.

Funding

School of Science, Monash University Higher Degree by Research (HDR) FundingSunway University Internal Research Grant 2019 INT-2019-SHMS-DMS-01
6 · The paper itself

Abstract

Challenges in organ transplantation such as high organ demand and biocompatibility issues have led scientists in the field of tissue engineering and regenerative medicine to work on the use of scaffolds as an alternative to transplantation. Among different types of scaffolds, polymeric hydrogel scaffolds have received considerable attention because of their biocompatibility and structural similarity to native tissues. However, hydrogel scaffolds have several limitations, such as weak mechanical property and a lack of bioactive property. On the other hand, noble metal particles, particularly gold (Au) and silver (Ag) nanoparticles (NPs), can be incorporated into the hydrogel matrix to form NP⁻hydrogel composite scaffolds with enhanced physical and biological properties. This review aims to highlight the potential of these hybrid materials in tissue engineering applications. Additionally, the main approaches that have been used for the synthesis of NP⁻hydrogel composites and the possible limitations and challenges associated with the application of these materials are discussed.

Indexed as

gold nanoparticlehydrogelnanocompositeregenerative medicinesilver nanoparticletissue engineering

Identifiers

PMID30754677
PMCPMC6466392

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.