Evidence map›Paper›PMID 30754666›Full record

ReviewMolecules (Basel, Switzerland)2019

Stereoselective Multicomponent Reactions in the Synthesis or Transformations of Epoxides and Aziridines.

Allan Ribeiro da Silva, Deborah Araujo Dos Santos, Marcio Weber Paixão, Arlene Gonçalves Corrêa

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 36 citations in OpenAlex.

  1. Synthesis ofChemical communications (Cambridge, England) · 2025
    Article
  2. Fused-Linked and Spiro-Linked N-Containing Heterocycles.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Allan Ribeiro da SilvaCentre of Excellence for Research in Sustainable Chemistry, Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil. allan.silva.bsb@hotmail.com.
Deborah Araujo Dos SantosCentre of Excellence for Research in Sustainable Chemistry, Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil. deborah.araujo89@gmail.com.
Marcio Weber PaixãoCentre of Excellence for Research in Sustainable Chemistry, Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil. mwpaixao@ufscar.br.
Arlene Gonçalves CorrêaCentre of Excellence for Research in Sustainable Chemistry, Department of Chemistry, Federal University of São Carlos, 13565-905 São Carlos, SP, Brazil. agcorrea@ufscar.br.
Universidade Federal de São Carlos · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302634/2016-9Conselho Nacional de Desenvolvimento Científico e Tecnológico 429748/2018-3Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/50249-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/23867-0Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/09961-7GlaxoSmithKline #
6 · The paper itself

Abstract

Small ring heterocycles, such as epoxides and aziridines, are present in several natural products and are also highly versatile building blocks, frequently involved in the synthesis of numerous bioactive products and pharmaceuticals. Because of the potential for increased efficiency and selectivity, along with the advantages of environmentally benign synthetic procedures, multicomponent reactions (MCRs) have been explored in the synthesis and ring opening of these heterocyclic units. In this review, the recent advances in MCRs involving the synthesis and applications of epoxides and aziridines to the preparation of other heterocycles are discussed emphasizing the stereoselectivity of the reactions.

Indexed as

AziridinesBiological ProductsEpoxy CompoundsGreen Chemistry TechnologyMolecular StructureStereoisomerismAziridinesBiological ProductsEpoxy Compoundsasymmetric synthesisaziridineepoxidesgreen synthesismulticomponent reactions

Identifiers

PMID30754666
PMCPMC6384726
OpenAlexW2912933012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.