Evidence map›Paper›PMID 30753972›Full record

ArticleAddictive behaviors2019

Cross-domain correlates of cannabis use disorder severity among young adults.

Randi Melissa Schuster, Maya Hareli, Amelia D Moser, Kelsey Lowman, Jodi Gilman, Christine Ulysse, David Schoenfeld, A Eden Evins

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Randi Melissa SchusterCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, Boston, MA, United States. Electronic address: Rschuster@mgh.harvard.edu.
Maya HareliCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States.
Amelia D MoserCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States.
Kelsey LowmanCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States.
Jodi GilmanCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, Boston, MA, United States.
Christine UlysseDepartment of Biostatistics, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
David SchoenfeldDepartment of Biostatistics, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
A Eden EvinsCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, Boston, MA, United States.
Harvard University · USMassachusetts General Hospital · US

Funding

Medical Marijuana, Neurocognition, and Subsequent Substance UseR01DA042043 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI GILMAN, JODI · 2017 to 2021
$3.3M
Mentoring in Addiction Treatment ResearchK24DA030443 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI EVINS, A EDEN · 2010 to 2020
$2.0M
Cognitive Recovery With Cannabis Abstinence Among High School-Aged AdolescentsK23DA042946 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI SCHUSTER, RANDI MELISSA · 2017 to 2021
$1.1M
Neurobehavioral Characterization of Social Influence in Drug AddictionK01DA034093 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI GILMAN, JODI · 2013 to 2017
$925k
NIDA NIH HHS K01 DA034093NIDA NIH HHS K23 DA042946NIDA NIH HHS K24 DA030443NIDA NIH HHS R01 DA042043
6 · The paper itself

Abstract

backgroundCorrelates of cannabis use and dependence among young adults have been widely studied. However, it is not known which factors are most strongly associated with severity of cannabis use dependence (CUD) severity. Identification of the salient correlates of CUD severity will be of increasing clinical significance as use becomes more socially normative.

methodsThis study used a data-driven, hypothesis-free approach to examine the most robust correlates of CUD severity among a sample of 76 young adults (ages 18 to 25 years) who used cannabis at least weekly. Seventy-one candidate variables were examined for association with CUD severity. These included demographic variables, self-reported and psychodiagnostic assessments of mood and anxiety, self-reported measures of personality, cannabis and other substance use characteristics, and objective and subjective measures of cognition.

resultsOf the 71 candidate variables considered, 27 were associated with CUD severity on a univariate level at a p-value ≤.20. Correlates of CUD severity in the multivariable model using stepwise selection were: more frequent cannabis use in the past 90 days, greater expectancies that cannabis causes cognitive and behavioral impairment, greater self-reported metacognitive deficits, greater anxiety, and lower reaction time variability on a test of sustained attention. Internal validation tests support high prediction accuracy of all variables in the multivariable model, except for lower reaction time variability.

conclusionsCannabis use frequency, beliefs about use, perceived cognitive abilities, and anxiety are robustly associated with CUD severity in young adult, regular cannabis users, and may be important in guiding prevention and treatment efforts.

Indexed as

AttentionMetacognitionMotivationAdolescentAdultAnxietyCognitionFemaleHumansMaleMarijuana AbuseMarijuana UseMultivariate AnalysisPeer GroupPersonalityReaction TimeCannabisCannabis dependenceYoung adults

Identifiers

PMID30753972
PMCPMC6920664
OpenAlexW2912840199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.