Evidence map›Paper›PMID 30753953›Full record

ArticleJournal of affective disorders2019

The relationship between past 12-month suicidality and reasons for prescription opioid misuse.

Lisham Ashrafioun, Sarah Heavey, Taraneh Canarapen, Todd M Bishop, Wilfred R Pigeon

Abstract read
In one paragraph

Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Prescription Drug Misuse: Taking a Lifespan Perspective.Substance abuse : research and treatment · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lisham AshrafiounDepartment of Psychiatry, University of Rochester Medical Center, USA; VA Center of Excellence for Suicide Prevention, Canandaigua VA Medical Center, USA. Electronic address: Lisham_ashrafioun@urmc.rochester.edu.
Sarah HeaveyDepartment of Psychiatry, University of Rochester Medical Center, USA.
Taraneh CanarapenMental Health Services, Canandaigua VA Medical Center, USA.
Todd M BishopDepartment of Psychiatry, University of Rochester Medical Center, USA; VA Center of Excellence for Suicide Prevention, Canandaigua VA Medical Center, USA.
Wilfred R PigeonDepartment of Psychiatry, University of Rochester Medical Center, USA; VA Center of Excellence for Suicide Prevention, Canandaigua VA Medical Center, USA.

Funding

Postdoctoral Training in Suicide Prevention Research (supplement 2)T32MH020061 · NIMH · UNIVERSITY OF ROCHESTER · PI VAN ORDEN, KIMBERLY ALLISON · 2001 to 2025
$5.9M
NIMH NIH HHS T32 MH020061
6 · The paper itself

Abstract

backgroundUnderstanding reasons for prescription opioid misuse can help elucidate suicide prevention efforts. The goal of the current study is to assess associations of reasons for prescription opioid misuse subtypes and suicide-related variables. We also assessed whether prescription opioid misuse differentiates ideators from those who attempt suicide.

methodsUsing data from the 2015-2017 National Survey of Drug Use and Health (N = 45,074), prescription opioid misuse subtypes were grouped as follows: (a) Pain only, (b) Other reasons, and (c) Mixed reasons (i.e., pain and at least one other reason). Logistic regressions examined associations of misuse subtypes and past 12-month suicide-related variables (ideation, planning, attempts) relative to non-misusers. Logistic regression analyses were also conducted among the subset reporting ideation to assess whether prescription opioid misuse differentiated ideators with no attempt from ideators with an attempt.

resultsIn adjusted models, the Pain only and the Other reasons subtypes were associated with ideation and planning, but not attempts. The Mixed reasons subtype had higher odds of suicide ideation and planning compared to those not misusing prescription opioids and the Pain only misuse subtype. The Mixed reasons subtype had higher odds of a suicide attempt only when compared to those not misusing prescription opioids. Prescription opioid misuse was also associated with suicide attempts among the subset of ideators.

conclusionsFindings indicate that people misuse prescription opioids for various reasons, and misuse subtypes are associated with past 12-month suicidality. Addressing pain and other reasons for misuse together through use of evidence-based treatments may help mitigate suicide risk.

Indexed as

Suicidal IdeationAdolescentAdultAgedFemaleHumansLogistic ModelsMaleMiddle AgedMotivationOpioid-Related DisordersPainPrescription Drug MisuseSuicide, AttemptedThinkingYoung AdultMotivesPrescription opioid misuseSubtypesSuicide attemptsSuicide ideation

Identifiers

PMID30753953
PMCPMC7870327

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.