ArticleNeuroImage2019
Quasi-periodic patterns contribute to functional connectivity in the brain.
Article in NeuroImage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
- Infraslow Closed-Loop Brain Training for Anxiety and Depression (ISAD): A pilot randomised, sham-controlled trial in adult females with internalizing disorders.Cognitive, affective & behavioral neuroscience · 2025Trial
- Thalamic modulation of cortical linearity across arousal states.Science advances · 2026Article
- The maintenance of attention over time influences the dynamics of EEG microstates.Cognitive, affective & behavioral neuroscience · 2026Article
- Three parsimonious spatiotemporal patterns in cerebellum reveal individual traits in function and behavior.Nature communications · 2026Article
- Cognition emerges from phase dynamics of intrinsic coordination.bioRxiv : the preprint server for biology · 2026Article
- Developmental variations in recurrent spatiotemporal brain propagations from childhood to adulthood.Nature communications · 2026Article
- Fidelity of Spatiotemporal Patterns of Brain Activity Across Sampling Rate, Scan Duration, and Frequency Content.bioRxiv : the preprint server for biology · 2026Article
- Time-resolved large-scale neural coactivations in macaque monkey.NeuroImage · 2025Article
- Ultrafast Imaging of Physiological Brain Pulsations With Magnetic Resonance Encephalography-From Noise to Predictive Clinical Biomarker.NMR in biomedicine · 2025Review
- Review
- Infraslow Dynamic Patterns in Human Cortical Networks Track a Spectrum of External to Internal Attention.Human brain mapping · 2025Article
- Article
- QPPLab: A generally applicable software package for detecting, analyzing, and visualizing large-scale quasiperiodic spatiotemporal patterns (QPPs) of brain activity.bioRxiv : the preprint server for biology · 2025Article
- Vasomotor fluctuations are increased in primary central nervous system lymphoma: a case-control study with fast functional MRI.Brain communications · 2025Article
- Altered functional connectivity and spatiotemporal dynamics in individuals with central disorders of hypersomnolence.Frontiers in neuroscience · 2025Article
- Older is order: entropy reduction in cortical spontaneous activity marks healthy aging.BMC neuroscience · 2024Article
- Evolutionarily conserved fMRI network dynamics in the mouse, macaque, and human brain.Nature communications · 2024Article
- Evolution of aberrant brain-wide spatiotemporal dynamics of resting-state networks in a Huntington's disease mouse model.Clinical and translational medicine · 2024Article
- Variation in the Distribution of Large-scale Spatiotemporal Patterns of Activity Across Brain States.bioRxiv : the preprint server for biology · 2024Article
- Infraslow dynamic patterns in human cortical networks track a spectrum of external to internal attention.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Functional connectivity is widely used to study the coordination of activity between brain regions over time. Functional connectivity in the default mode and task positive networks is particularly important for normal brain function. However, the processes that give rise to functional connectivity in the brain are not fully understood. It has been postulated that low-frequency neural activity plays a key role in establishing the functional architecture of the brain. Quasi-periodic patterns (QPPs) are a reliably observable form of low-frequency neural activity that involve the default mode and task positive networks. Here, QPPs from resting-state and working memory task-performing individuals were acquired. The spatiotemporal pattern, strength, and frequency of the QPPs between the two groups were compared and the contribution of QPPs to functional connectivity in the brain was measured. In task-performing individuals, the spatiotemporal pattern of the QPP changes, particularly in task-relevant regions, and the QPP tends to occur with greater strength and frequency. Differences in the QPPs between the two groups could partially account for the variance in functional connectivity between resting-state and task-performing individuals. The QPPs contribute strongly to connectivity in the default mode and task positive networks and to the strength of anti-correlation seen between the two networks. Many of the connections affected by QPPs are also disrupted during several neurological disorders. These findings contribute to understanding the dynamic neural processes that give rise to functional connectivity in the brain and how they may be disrupted during disease.
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