Evidence map›Paper›PMID 30753725›Full record

ArticleSchizophrenia bulletin2019

Common Taxonomy of Traits and Symptoms: Linking Schizophrenia Symptoms, Schizotypy, and Normal Personality.

David C Cicero, Katherine G Jonas, Kaiqiao Li, Greg Perlman, Roman Kotov

Abstract read
In one paragraph

Article in Schizophrenia bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Personality domains in early stages of psychosis: a systematic review and meta-analysis.European archives of psychiatry and clinical neuroscience · 2026
    Pooled it
  2. Pooled it
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  10. Reconstructing Psychopathology: A Data-Driven Reorganization of the Symptoms in the Diagnostic and Statistical Manual of Mental Disorders.Clinical psychological science : a journal of the Association for Psychological Science · 2025
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  12. Article
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  19. Conceptualizing a less paranoid schizophrenia.Philosophy, ethics, and humanities in medicine : PEHM · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David C CiceroDepartment of Psychology, University of Hawaii at Manoa, Honolulu, HI.
Katherine G JonasDepartment of Psychiatry, Stony Brook University, Stony Brook, NY.
Kaiqiao LiDepartment of Psychiatry, Stony Brook University, Stony Brook, NY.
Greg PerlmanDepartment of Psychiatry, Stony Brook University, Stony Brook, NY.
Roman KotovDepartment of Psychiatry, Stony Brook University, Stony Brook, NY.

Funding

THE EPIDEMIOLOGY OF NEWLY DIAGNOSED PSYCHOTIC DISORDERSR01MH044801 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI BROMET, EVELYN J · 1989 to 2007
$5.0M
Trajectories of Aging in Psychotic Disorders Over 27 YearsR01MH110434 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KOTOV, ROMAN I · 2016 to 2020
$4.5M
Trajectories of recovery from psychosis over two decadesR01MH094398 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI KOTOV, ROMAN I · 2011 to 2013
$2.2M
NIMH NIH HHS R01 MH044801NIMH NIH HHS R01 MH094398NIMH NIH HHS R01 MH110434
6 · The paper itself

Abstract

The associations among normal personality and many mental disorders are well established, but it remains unclear whether and how symptoms of schizophrenia and schizotypal traits align with the personality taxonomy. This study examined the joint factor structure of normal personality, schizotypy, and schizophrenia symptoms in people with psychotic disorders (n = 288) and never-psychotic adults (n = 257) in the Suffolk County Mental Health Project. First, we evaluated the structure of schizotypal (positive schizotypy, negative schizotypy, and mistrust) and normal traits. In both the psychotic-disorder and never-psychotic groups, the best-fitting model had 5 factors: neuroticism, extraversion, conscientiousness, agreeableness, and psychoticism. The schizotypy traits were placed on different dimensions: negative schizotypy went on (low) extraversion, whereas positive schizotypy and mistrust went on psychoticism. Next, we added symptoms to the model. Numerous alternatives were compared, and the 5-factor model remained best-fitting. Reality distortion (hallucinations and delusions) and disorganization symptoms were placed on psychoticism, and negative symptoms were placed on extraversion. Models that separated symptom dimensions from trait dimensions did not fit well, arguing that taxonomies of symptoms and traits are aligned. This is the first study to show that symptoms of psychosis, schizotypy, and normal personality reflect the same underlying dimensions. Specifically, (low) extraversion, negative schizotypy, and negative symptoms form one spectrum, whereas psychoticism, positive schizotypy, and positive and disorganized symptoms form another. This framework helps to understand the heterogeneity of psychosis and comorbidity patterns found in psychotic disorders. It also underscores the importance of traits to understanding these disorders.

Indexed as

Extraversion, PsychologicalNeuroticismPersonalitySchizophrenic PsychologyAdultBipolar DisorderCase-Control StudiesClassificationFemaleHumansMajor Depressive DisorderMaleMiddle AgedPsychotic DisordersSchizophreniaSchizotypal Personality Disorderdetachmentmistrustnegative symptomspositive symptomspsychoticism

Identifiers

PMID30753725
PMCPMC6811822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.