ArticleSchizophrenia bulletin2019
Cortical Contributions to Distinct Symptom Dimensions of Catatonia.
Article in Schizophrenia bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Functional neuroimaging in patients with catatonia: A systematic review.Journal of psychosomatic research · 2024Pooled it
- [The sensorimotor domain in the research domain criteria system: progress and perspectives].Der Nervenarzt · 2021Pooled it
- Going Back to Kahlbaum's Psychomotor (and GABAergic) Origins: Is Catatonia More Than Just a Motor and Dopaminergic Syndrome?Schizophrenia bulletin · 2020Pooled it
- Frozen emotions, frozen bodies: a systematic review of limbic system alterations in catatonia.European archives of psychiatry and clinical neuroscience · 2026Review
- Schizophrenia and disordered sensorimotor control: challenges, mechanisms and opportunities.Brain : a journal of neurology · 2026Review
- Parkinsonism, Psychomotor Slowing, Negative and Depressive Symptoms in Schizophrenia Spectrum and Mood Disorders: Exploring Their Intricate Nexus Using a Network Analytic Approach.Schizophrenia bulletin · 2025Article
- Deciphering the interplay between psychopathological symptoms, sensorimotor, cognitive and global functioning: a transdiagnostic network analysis.European archives of psychiatry and clinical neuroscience · 2024Article
- Unraveling the enigma of 'Psychological Pillow': A unique catatonic phenomenon.Industrial psychiatry journal · 2024Article
- Catatonia.Nature reviews. Disease primers · 2024Review
- Is depression a global brain disorder with topographic dynamic reorganization?Translational psychiatry · 2024Review
- Orbitofrontal sulcal patterns in catatonia.European psychiatry : the journal of the Association of European Psychiatrists · 2023Article
- Review
- Different faces of catatonia and how to approach them.European archives of psychiatry and clinical neuroscience · 2022Article
- Resting state functional connectivity and structural abnormalities of the brain in acute retarded catatonia: an exploratory MRI study.European archives of psychiatry and clinical neuroscience · 2022Article
- Characterizing the sensorimotor domain in schizophrenia spectrum disorders.European archives of psychiatry and clinical neuroscience · 2022Article
- Hypogyrification in Generalized Anxiety Disorder and Associated with Insomnia Symptoms.Nature and science of sleep · 2022Article
- Altered Spontaneous Brain Activity Patterns of Meibomian Gland Dysfunction in Severely Obese Population Measured Using the Fractional Amplitude of Low-Frequency Fluctuations.Frontiers in psychiatry · 2022Article
- Molecular and cellular mechanisms leading to catatonia: an integrative approach from clinical and preclinical evidence.Frontiers in molecular neuroscience · 2022Review
- Mechanistic modeling as an explanatory tool for clinical treatment of chronic catatonia.Frontiers in pharmacology · 2022Article
- Intrinsic neural network dynamics in catatonia.Human brain mapping · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Catatonia is a central aspect of schizophrenia spectrum disorders (SSD) and most likely associated with abnormalities in affective, motor, and sensorimotor brain regions. However, contributions of different cortical features to the pathophysiology of catatonia in SSD are poorly understood. Here, T1-weighted structural magnetic resonance imaging data at 3 T were obtained from 56 right-handed patients with SSD. Using FreeSurfer version 6.0, we calculated cortical thickness, area, and local gyrification index (LGI). Catatonic symptoms were examined on the Northoff catatonia rating scale (NCRS). Patients with catatonia (NCRS total score ≥3; n = 25) showed reduced surface area in the parietal and medial orbitofrontal gyrus and LGI in the temporal gyrus (P < .05, corrected for cluster-wise probability [CWP]) as well as hypergyrification in rostral cingulate and medial orbitofrontal gyrus when compared with patients without catatonia (n = 22; P < .05, corrected for CWP). Following a dimensional approach, a negative association between NCRS motor and behavior scores and cortical thickness in superior frontal, insular, and precentral cortex was found (34 patients with at least 1 motor and at least 1 other affective or behavioral symptom; P < .05, corrected for CWP). Positive associations were found between NCRS motor and behavior scores and surface area and LGI in superior frontal, posterior cingulate, precentral, and pericalcarine gyrus (P < .05, corrected for CWP). The data support the notion that cortical features of distinct evolutionary and genetic origin differently contribute to catatonia in SSD. Catatonia in SSD may be essentially driven by cortex variations in frontoparietal regions including regions implicated in the coordination and goal-orientation of behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.