ArticleNeuro-oncology2019
Cognitive outcomes in meningioma patients undergoing surgery: individual changes over time and predictors of late cognitive functioning.
Article in Neuro-oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The unseen impact - a deep dive into neurocognitive impairment among patients with intracranial meningiomas: a comprehensive systematic review of the literature.Neurosurgical review · 2024Pooled it
- EANO guideline on the diagnosis and management of meningiomas.Neuro-oncology · 2021Guideline
- eHealth cognitive rehabilitation for brain tumor patients: results of a randomized controlled trial.Journal of neuro-oncology · 2021Trial
- Variety of Neuropsychological Deficits and Clinical Rehabilitation Course After Surgical Removal of Cerebral Meningioma Under Neuropsychological Therapy.Brain sciences · 2026Article
- Reliable cognitive changes the first year following guideline-based treatment of isocitrate dehydrogenase mutated gliomas: A longitudinal multicenter study.Neuro-oncology · 2026Article
- Mapping Cognitive Oncology: A Decade of Trends and Research Fronts.Medical sciences (Basel, Switzerland) · 2025Review
- Neuropsychological Aspects of a Patient With Intracranial Rosai-Dorfman Disease: Case Report.Clinical case reports · 2025Article
- Comparison of Subjective and Objective Cognitive Function and Emotional State in Supratentorial Brain Tumors Before Surgery-Recognizing the Influence of Laterality.Cancer medicine · 2025Article
- Skull-meninges-brain connectivity and extra-axial brain tumours.Brain communications · 2025Review
- Neurocognitive evaluation in patients with intracranial Meningiomas: A systematic review.Brain & spine · 2025Review
- Independent and combined associations of VOCs exposure and MetS in theFrontiers in public health · 2025Article
- Surgical treatment of meningiomas improves neurocognitive functioning and quality of life - a prospective single-center study.Acta neurochirurgica · 2024Article
- Preoperative executive functioning impairments in patients with a meningioma: does a frontal location matter?Brain imaging and behavior · 2024Article
- Predicting Cognitive Functioning for Patients with a High-Grade Glioma: Evaluating Different Representations of Tumor Location in a Common Space.Neuroinformatics · 2024Article
- Modern Radiation Treatment Planning Parameters and Outcomes in Pediatric Tectal Gliomas.Advances in radiation oncology · 2024Article
- Long-term neurocognitive and psychological outcomes in meningioma survivors: Individual changes over time and radiation dosimetry.Neuro-oncology practice · 2024Article
- Multiple meningiomas: Epidemiology, management, and outcomes.Neuro-oncology advances · 2023Article
- Health-Related Quality of Life in Intracranial Meningioma: Current Evidence and Future Directions.Advances in experimental medicine and biology · 2023Article
- Processing efficiency in pediatric cancer survivors: A review and operationalization for outcomes research and clinical utility.Brain and behavior · 2022Review
- Radiation dose to circumscribed brain regions and neurocognitive function in patients with meningioma.Neuro-oncology practice · 2022Article
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7 authors.
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Abstract
backgroundMeningioma patients are known to face cognitive deficits before and after surgery. We examined individual changes in cognitive performance over time and identified preoperative predictors of cognitive functioning 12 months after surgery in a large sample of meningioma patients.
methodsPatients underwent neuropsychological assessment (NPA) using CNS Vital Signs 1 day before (T0) and 3 (T3) and 12 (T12) months after surgery. Patients' sociodemographically corrected scores on 7 cognitive domains were compared with performance of a normative sample using one-sample z tests and chi-square tests of independence. Reliable change indices with correction for practice effects were calculated for individual patients. Linear mixed effects models were used to identify preoperative predictors of performance at T12.
resultsAt T0, 261 patients were assessed, and 229 and 82 patients were retested at T3 and T12, respectively. Patients showed impaired cognitive performance before and after surgery, and although performance improved on the group level, cognitive scores remained significantly lower than in the normative sample up to T12. On the individual level, performance remained stable in the majority of patients. Better preoperative performance, younger age, male sex, and higher educational level predicted better late cognitive performance.
conclusionsMeningioma patients face serious and persistent pre- and postsurgical cognitive deficits. A preoperative NPA together with sociodemographic characteristics may provide valuable information on the late cognitive outcome of individual meningioma patients. These results can help to inform patients and clinicians on late cognitive outcomes at an early stage, and emphasizes the importance of presurgical NPA and timely cognitive rehabilitation.
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