ArticleJournal of experimental botany2019
Extracellular peptide Kratos restricts cell death during vascular development and stress in Arabidopsis.
Article in Journal of experimental botany, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Root hair lifespan is antagonistically controlled by autophagy and programmed cell death.Nature plants · 2026Article
- Phytosulfokine signalling blocks mycotoxin toxicity in Arabidopsis and mediates suppression of cell death activated by bacterial microbe-associated molecular patterns.The New phytologist · 2026Article
- Phosphoenolpyruvate and Related Metabolic Pathways Contribute to the Regulation of Plant Growth and Development.International journal of molecular sciences · 2025Review
- Insights ofFrontiers in plant science · 2025Article
- Streamlined spatial and environmental expression signatures characterize the minimalist duckweedGenome research · 2024Article
- Review
- Differentially Expressed Genes Shared by Two Distinct Cytoplasmic Male Sterility (CMS) Types ofCells · 2020Article
- Breaking Bad News: Dynamic Molecular Mechanisms of Wound Response in Plants.Frontiers in plant science · 2020Review
- ThePlant direct · 2019Article
- Plant proteases and programmed cell death.Journal of experimental botany · 2019Article
- The Arabidopsis thaliana METACASPASE IIf Regulates Sugar Metabolism and Delays Dark-Induced Leaf Senescence.Physiologia plantarumArticle
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During plant vascular development, xylem tracheary elements (TEs) form water-conducting, empty pipes by genetically regulated cell death. Cell death is prevented from spreading to non-TEs by unidentified intercellular mechanisms, downstream of METACASPASE9 (MC9)-mediated regulation of autophagy in TEs. Here, we identified differentially abundant extracellular peptides in vascular-differentiating wild-type and MC9-down-regulated Arabidopsis cell suspensions. A peptide named Kratos rescued the abnormally high ectopic non-TE death resulting from either MC9 knockout or TE-specific overexpression of the ATG5 autophagy protein during experimentally induced vascular differentiation in Arabidopsis cotyledons. Kratos also reduced cell death following mechanical damage and extracellular ROS production in Arabidopsis leaves. Stress-induced but not vascular non-TE cell death was enhanced by another identified peptide, named Bia. Bia is therefore reminiscent of several known plant cell death-inducing peptides acting as damage-associated molecular patterns. In contrast, Kratos plays a novel extracellular cell survival role in the context of development and during stress response.
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